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Go!
YARS [cytosol]
Stable Identifier
R-HSA-379560
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Tyrosyl-tRNA synthetase
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
tRNA Aminoacylation (Homo sapiens)
Cytosolic tRNA aminoacylation (Homo sapiens)
tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate (Homo sapiens)
YARS dimer [cytosol] (Homo sapiens)
YARS [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P54577 YARS1
Gene Names
YARS1, YARS
Chain
chain:1-528, initiator methionine:, chain:2-528
Reference Genes
BioGPS Gene:8565 YARS1
CTD Gene:8565 YARS1
dbSNP Gene:8565 YARS1
ENSEMBL:ENSG00000134684 YARS
ENSEMBL_homo_sapiens_GENE:ENSG00000134684.13 YARS1
HGNC:12840 YARS1
KEGG Gene (Homo sapiens):8565 YARS1
Monarch:8565 YARS1
NCBI Gene:8565 YARS1
OMIM:603623 YARS1
UCSC:P54577 YARS1
Reference Transcript
RefSeq:NM_003680.3 YARS1
Other Identifiers
11758118_s_at
16684760
212048_PM_s_at
212048_s_at
2405193
2405194
2405195
2405196
2405197
2405198
2405199
2405201
2405202
2405206
2405208
2405212
2405214
2405218
2405221
2405222
2405225
2405227
2405228
2405231
38977_at
7914563
8565
A_23_P379550
GE61991
GO:0000049
GO:0000166
GO:0003723
GO:0003824
GO:0004812
GO:0004831
GO:0005153
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006399
GO:0006412
GO:0006418
GO:0006437
GO:0006520
GO:0006915
GO:0012501
GO:0016604
GO:0016874
GO:0036094
GO:0042594
GO:0043226
GO:0140098
HMNXSV003048456
Hs.239307.1.A2_3p_a_at
ILMN_1766010
PH_hs_0029468
TC01002475.hg
U40714_at
Participates
as a component of
YARS dimer [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_003671.1
OpenTargets
ENSG00000134684
ZINC - Substances
SYYC_HUMAN
ZINC target
P54577
ZINC - Biogenic
SYYC_HUMAN
PRO
P54577
PDB
1N3L
,
4Q93
,
5THH
,
5THL
,
1Q11
,
4QBT
,
1NTG
,
7ROU
ZINC - Metabolites
SYYC_HUMAN
HPA
ENSG00000134684-YARS1
GeneCards
P54577
Ensembl
ENST00000373477
,
ENSP00000362576
,
ENSG00000134684
Pharos - Targets
P54577
ZINC - Predictions - Purchasable
SYYC_HUMAN
Orphanet
16932
HMDB Protein
HMDBP00606
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75925 PIAS1
1
PIAS1 [nucleoplasm]
(R-HSA-877307)
0.556
3
UniProt:P09874 PARP1
4
polySUMO2,3-K203,K486-PARP1 [nucleoplasm]
(R-HSA-4551617)
monoSUMO1-K203,K486-PARP1 [nucleoplasm]
(R-HSA-4551686)
PAR-PARP1 [nucleoplasm]
(R-HSA-5651713)
PARP1 [nucleoplasm]
(R-HSA-201568)
0.524
5
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