Reactome | SLC7A7 [plasma membrane]

SLC7A7 [plasma membrane]

Stable Identifier

R-HSA-379417

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Y+L amino acid transporter 1

Locations in the PathwayBrowser

Expand all

Hemostasis (Homo sapiens)

- Cell surface interactions at the vascular wall (Homo sapiens)
  - Basigin interactions (Homo sapiens)
    - Basigin binds CD98 complex (Homo sapiens)
      - Basigin:CD98hc complex [plasma membrane] (Homo sapiens)
        
        CD98hc complex [plasma membrane] (Homo sapiens)
        
        SLC7A7:SLC3A2 heterodimer [plasma membrane] (Homo sapiens)
        
        SLC7A7 [plasma membrane] (Homo sapiens)
      - CD98hc complex [plasma membrane] (Homo sapiens)
        
        SLC7A7:SLC3A2 heterodimer [plasma membrane] (Homo sapiens)
        
        SLC7A7 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9UM01 SLC7A7

Gene Names

SLC7A7

Chain

chain:1-511

Reference Genes

BioGPS Gene:9056 SLC7A7

COSMIC (genes):SLC7A7 SLC7A7

CTD Gene:9056 SLC7A7

dbSNP Gene:9056 SLC7A7

ENSEMBL:ENSG00000155465 SLC7A7

HGNC:11065 SLC7A7

KEGG:hsa:9056 SLC7A7

Monarch:9056 SLC7A7

NCBI Gene:9056 SLC7A7

OMIM:603593 SLC7A7

UCSC:Q9UM01 SLC7A7

Reference Transcript

Other Identifiers

11720989_a_at

204588_PM_s_at

204588_s_at

33731_at

3556817

3556818

3556819

3556820

3556821

3556822

3556823

3556825

3556826

3556827

3556828

3556829

3556830

3556831

3556837

3556838

3556839

3556840

3556841

3556842

3556843

3556844

3556845

3556846

3556847

3556848

7977786

9056

A_23_P99642

GE55209

GO:0000821

GO:0003333

GO:0005215

GO:0005515

GO:0005886

GO:0006865

GO:0015174

GO:0015179

GO:0015820

GO:0016020

GO:0016323

GO:0022857

GO:0055085

GO:0061459

GO:1902475

GO:1903826

GO:1990822

HMNXSV003020439

ILMN_1810275

PH_hs_0011505

TC14000936.hg

TC14000937.hg

TC14001926.hg

g4507054_3p_a_at

Participates

as a component of

SLC7A7:SLC3A2 heterodimer [plasma membrane] (Homo sapiens)

Other forms of this molecule

SLC7A7 T188I [plasma membrane]

SLC7A7 M50K [plasma membrane]

SLC7A7 T299Ifs*10 [plasma membrane]

SLC7A7 W242* [plasma membrane]

SLC7A7 L334R [plasma membrane]

SLC7A7 Y457* [plasma membrane]

Inferred To

Homologues of SLC7A7 [plasma membrane] (Drosophila melanogaster)

SLC7A7 [plasma membrane] (Bos taurus)

SLC7A7 [plasma membrane] (Sus scrofa)

Dmel\CG1607 [plasma membrane] (Drosophila melanogaster)

Slc7a7 [plasma membrane] (Mus musculus)

Slc7a7 [plasma membrane] (Rattus norvegicus)

slc7a7 [plasma membrane] (Danio rerio)

slc7a7 [plasma membrane] (Xenopus tropicalis)

gb [plasma membrane] (Drosophila melanogaster)

mnd [plasma membrane] (Drosophila melanogaster)

JhI-21 [plasma membrane] (Drosophila melanogaster)

Cross References

Guide to Pharmacology - Targets

898

OpenTargets

ENSG00000155465

ENSEMBL

ENST00000397532, ENST00000674313, ENSG00000155465, ENST00000285850, ENST00000555911, ENST00000555702, ENSP00000285850, ENSP00000380666, ENSP00000380662, ENSP00000380663, ENST00000397529, ENST00000397528, ENSP00000501493, ENSP00000452551, ENSP00000451881

HPA

ENSG00000155465-SLC7A7

GeneCards

SLC7A7

PRO

Q9UM01

Pharos - Targets

Q9UM01

Orphanet

SLC7A7

GlyGen

Q9UM01

HMDB Protein

HMDBP03080