Reactome | PCSK1 [secretory granule lumen]

PCSK1 [secretory granule lumen]

Stable Identifier

R-HSA-378951

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

secretory granule lumen

Synonyms

Neuroendocrine convertase 1, NEC1_HUMAN

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External Reference Information

External Reference

UniProt:P29120 PCSK1

Gene Names

PCSK1, NEC1

Chain

signal peptide:1-27, propeptide:28-110, chain:111-753

Reference Genes

BioGPS Gene:5122 PCSK1

COSMIC (genes):PCSK1 PCSK1

CTD Gene:5122 PCSK1

dbSNP Gene:5122 PCSK1

ENSEMBL:ENSG00000175426 PCSK1

HGNC:8743 PCSK1

KEGG:hsa:5122 PCSK1

Monarch:5122 PCSK1

NCBI Gene:5122 PCSK1

OMIM:162150 PCSK1

UCSC:P29120 PCSK1

Reference Transcript

Other Identifiers

11736339_a_at

11736340_a_at

11756720_a_at

16998342

205825_PM_at

205825_at

2868045

2868046

2868047

2868048

2868050

2868052

2868053

2868054

2868055

2868057

2868060

2868061

2868064

2868065

2868066

2868067

2868069

2868070

2868071

2868072

2868073

40649_at

5122

8113234

A_23_P213508

A_24_P174793

GE59910

GO:0003824

GO:0004175

GO:0004252

GO:0005615

GO:0005737

GO:0005802

GO:0006508

GO:0007267

GO:0008236

GO:0009410

GO:0009749

GO:0010157

GO:0014070

GO:0016020

GO:0016485

GO:0016486

GO:0016540

GO:0016787

GO:0021983

GO:0022008

GO:0023052

GO:0030070

GO:0030133

GO:0030141

GO:0030154

GO:0030425

GO:0031016

GO:0031410

GO:0031667

GO:0032496

GO:0034774

GO:0042802

GO:0043005

GO:0043025

GO:0043043

GO:0043204

GO:0043226

GO:0043231

GO:0043434

GO:0043679

GO:0048471

GO:0048678

GO:0048856

GO:0050714

GO:0051384

GO:0051592

GO:0051604

GO:0070542

GO:0070555

GO:0140096

HMNXSV003025228

ILMN_1710859

ILMN_2081813

PH_hs_0027701

TC05001614.hg

TC05003154.hg

X64810_at

g4585713_3p_at

g4585713_3p_x_at

Participates

as a component of

PC1:calcium cofactor [secretory granule lumen] (Homo sapiens)

Inferred To

PCSK1 [secretory granule lumen] (Bos taurus)

PCSK1 [secretory granule lumen] (Canis familiaris)

PCSK1 [secretory granule lumen] (Gallus gallus)

PCSK1 [secretory granule lumen] (Sus scrofa)

Pcsk1 [secretory granule lumen] (Mus musculus)

Pcsk1 [secretory granule lumen] (Rattus norvegicus)

pcsk1 [secretory granule lumen] (Danio rerio)

Cross References

RefSeq

NP_000430.3, NP_001171346.1

Guide to Pharmacology - Targets

2382

ENSEMBL

ENST00000508626, ENSP00000308024, ENSP00000421600, ENSG00000175426, ENST00000311106

OpenTargets

ENSG00000175426

ZINC - Substances

NEC1_HUMAN

ZINC target

P29120

PRO

P29120

GlyGen

P29120

GeneCards

PCSK1

HPA

ENSG00000175426-PCSK1

Pharos - Targets

P29120

Orphanet

PCSK1

ZINC - Predictions - Purchasable

NEC1_HUMAN

HMDB Protein

HMDBP07838