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IL6 gene [nucleoplasm]
Stable Identifier
R-HSA-3788729
Type
DNA Sequence [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
Senescence-Associated Secretory Phenotype (SASP) (Homo sapiens)
Activated CEBPB and NFKB complex bind IL6 promoter (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL6 gene [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
EHMT1:EHMT2 methylates IL6 promoter (Homo sapiens)
IL6 gene:Nucleosome [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
IL6 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
Regulation of IL6 transcription (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
VENTX:IL6 Gene [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL6 gene [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
ADORA2B mediated anti-inflammatory cytokines production (Homo sapiens)
CREB binds IL6 promoter (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
p-S133-CREB1:IL6 gene [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
IL6 gene produces IL6 protein (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
p-S133-CREB1:IL6 gene [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by VENTX (Homo sapiens)
Activated CEBPB and NFKB complex bind IL6 promoter (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL6 gene [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
Regulation of IL6 transcription (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
VENTX:IL6 Gene [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL6 gene [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
VENTX binds the IL6 gene promoter (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
VENTX:IL6 Gene [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-10 signaling (Homo sapiens)
IL10 negatively regulates extracellular inflammatory mediators (Homo sapiens)
IL10-downregulated genes for extracellular proteins [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
Interleukin-4 and Interleukin-13 signaling (Homo sapiens)
Expression of IL4,IL13-downregulated extracellular genes (Homo sapiens)
IL4,IL13-downregulated genes for extracellular proteins [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
Expression of STAT3-upregulated extracellular proteins (Homo sapiens)
STAT3-upregulated genes for extracellular proteins [nucleoplasm] (Homo sapiens)
IL6 gene [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
ENSEMBL:ENSG00000136244 IL6
Gene Names
IL6, IFNB2
Participates
as a member of
IL4,IL13-downregulated genes for extracellular proteins [nucleoplasm] (Homo sapiens)
STAT3-upregulated genes for extracellular proteins [nucleoplasm] (Homo sapiens)
IL10-downregulated genes for extracellular proteins [nucleoplasm] (Homo sapiens)
as an input of
CREB binds IL6 promoter (Homo sapiens)
IL6 gene produces IL6 protein (Homo sapiens)
VENTX binds the IL6 gene promoter (Homo sapiens)
Regulation of IL6 transcription (Homo sapiens)
Activated CEBPB and NFKB complex bind IL6 promoter (Homo sapiens)
as a component of
p-S133-CREB1:IL6 gene [nucleoplasm] (Homo sapiens)
IL6 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Homo sapiens)
IL6 gene:Nucleosome [nucleoplasm] (Homo sapiens)
VENTX:IL6 Gene [nucleoplasm] (Homo sapiens)
p-T235,S321-CEBPB:NF-kB:IL6 gene [nucleoplasm] (Homo sapiens)
Inferred To
Ghost homologue of IL6 gene [nucleoplasm]
(Bos taurus)
Ghost homologue of IL6 gene [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of IL6 gene [nucleoplasm]
(Canis familiaris)
Ghost homologue of IL6 gene [nucleoplasm]
(Danio rerio)
Ghost homologue of IL6 gene [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of IL6 gene [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of IL6 gene [nucleoplasm]
(Gallus gallus)
Ghost homologue of IL6 gene [nucleoplasm]
(Plasmodium falciparum)
Ghost homologue of IL6 gene [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of IL6 gene [nucleoplasm]
(Saccharomyces cerevisiae)
Ghost homologue of IL6 gene [nucleoplasm]
(Schizosaccharomyces pombe)
Ghost homologue of IL6 gene [nucleoplasm]
(Sus scrofa)
Ghost homologue of IL6 gene [nucleoplasm]
(Xenopus tropicalis)
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