Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Author/Reviewer Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
User Guide
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
Data Model
Computational inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Author/Reviewer Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Download
Search ...
Go!
DNA DSBs:MRN:ATM dimer:KAT5
Stable Identifier
R-HSA-3785779
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cellular responses to external stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
DNA Damage/Telomere Stress Induced Senescence (Homo sapiens)
KAT5 acetylates ATM at DNA DSBs (Homo sapiens)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Homo sapiens)
MRN complex bound to DNA ends recruits ATM (Homo sapiens)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Homo sapiens)
DNA Repair (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
DNA Double Strand Break Response (Homo sapiens)
Sensing of DNA Double Strand Breaks (Homo sapiens)
KAT5 acetylates ATM at DNA DSBs (Homo sapiens)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Homo sapiens)
MRN complex bound to DNA ends recruits ATM (Homo sapiens)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
17694070
MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control
Nat. Struct. Mol. Biol.
2007
15790808
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
Science
2005
Participants
components
dimeric ATM kinase [nucleoplasm] (Homo sapiens)
DNA DSBs:MRN [nucleoplasm] (Homo sapiens)
KAT5 [nucleoplasm] (Homo sapiens)
Participant Of
input
KAT5 acetylates ATM at DNA DSBs
output
MRN complex bound to DNA ends recruits ATM
Inferred To
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Arabidopsis thaliana)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Bos taurus)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Caenorhabditis elegans)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Canis familiaris)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Danio rerio)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Drosophila melanogaster)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Gallus gallus)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Mus musculus)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Oryza sativa)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Rattus norvegicus)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Saccharomyces cerevisiae)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Schizosaccharomyces pombe)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Sus scrofa)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Taeniopygia guttata)
DNA DSBs:MRN:ATM dimer:KAT5 [nucleoplasm] (Xenopus tropicalis)
© 2018
Reactome
