K48polyUb-EPM2A [cytosol]

Stable Identifier
R-HSA-3781004
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
K48polyUb-Laforin
Icon
K48polyUb-EPM2A [cytosol] icon
K48polyUb-EPM2A [cytosol] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
15930137 Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin

Gentry, MS, Worby, CA, Dixon, JE

Proc. Natl. Acad. Sci. U.S.A. 2005
External Reference Information
External Reference
UniProt:O95278 EPM2A
Gene Names
EPM2A
Chain
chain:1-331
Reference Genes
BioGPS Gene:7957 EPM2A
COSMIC (genes):EPM2A EPM2A
CTD Gene:7957 EPM2A
dbSNP Gene:7957 EPM2A
ENSEMBL:ENSG00000112425.16 EPM2A
KEGG Gene (Homo sapiens):7957 EPM2A
Monarch:7957 EPM2A
NCBI Gene:7957 EPM2A
OMIM:607566 EPM2A
UCSC:O95278 EPM2A
Reference Transcript
Other Identifiers
0000380162
11726414_a_at
11742276_a_at
11757797_s_at
205231_3p_s_at
205231_PM_s_at
205231_s_at
210870_PM_s_at
210870_s_at
2977964
2977965
2977966
2977967
2977968
2977969
2977970
2977971
2977972
2977973
2977981
2977982
2977983
2977991
2977992
2977993
2977994
2977995
2977996
2978001
2978002
2978003
2978004
2978005
34249_at
72754_at
7957
8130013
A_23_P170600
A_24_P239419
GE55211
GO:0000045
GO:0001558
GO:0001932
GO:0004373
GO:0004721
GO:0004722
GO:0004725
GO:0005515
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005789
GO:0005829
GO:0005844
GO:0005886
GO:0005975
GO:0005977
GO:0005978
GO:0006073
GO:0006091
GO:0006470
GO:0006816
GO:0006886
GO:0006913
GO:0006914
GO:0007005
GO:0007399
GO:0008138
GO:0010468
GO:0010629
GO:0010923
GO:0014009
GO:0015813
GO:0016020
GO:0016055
GO:0016239
GO:0016311
GO:0016740
GO:0016787
GO:0016791
GO:0017018
GO:0019203
GO:0023052
GO:0030154
GO:0030163
GO:0030246
GO:0030247
GO:0030425
GO:0031396
GO:0032991
GO:0033137
GO:0035305
GO:0035335
GO:0036211
GO:0042306
GO:0042325
GO:0042802
GO:0042803
GO:0043161
GO:0043204
GO:0043226
GO:0043231
GO:0044260
GO:0045786
GO:0045859
GO:0046835
GO:0046838
GO:0046959
GO:0046983
GO:0048856
GO:0050877
GO:0055085
GO:0061136
GO:0072659
GO:0098554
GO:0098556
GO:0140096
GO:1903076
GO:1904666
GO:2000465
GO:2001069
GO:2001070
HMNXSV003013724
HMNXSV003032263
ILMN_1719468
ILMN_1788156
PH_hs_0026362
PH_hs_0033913
g11321612_3p_a_at
g11321612_3p_s_at
g13528989_3p_a_at
Participates
as an output of
Other forms of this molecule
EPM2A F84L [cytosol]
EPM2A T194I [cytosol]
EPM2A P301L [cytosol]
EPM2A [cytosol]
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at unknown position
Modification
K48polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
OpenTargets
GeneCards
HPA
ZINC target
Ensembl
PRO
Pharos - Targets
Orphanet
PDB
HMDB Protein
Interactors (2)
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