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KRM1 [plasma membrane]
Stable Identifier
R-HSA-3769329
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
KREMEN1
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by WNT in cancer (Homo sapiens)
Signaling by LRP5 mutants (Homo sapiens)
misspliced mutants of LRP5 support enhanced beta-catenin-dependent signaling (Homo sapiens)
KRM1/2 [plasma membrane] (Homo sapiens)
KRM1 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Negative regulation of TCF-dependent signaling by WNT ligand antagonists (Homo sapiens)
DKK and KRM bind LRP5/6 (Homo sapiens)
KRM1/2 [plasma membrane] (Homo sapiens)
KRM1 [plasma membrane] (Homo sapiens)
KRM:DKK:LRP5/6 [plasma membrane] (Homo sapiens)
KRM1/2 [plasma membrane] (Homo sapiens)
KRM1 [plasma membrane] (Homo sapiens)
DKK promotes clathrin-dependent internalization of LRP6 (Homo sapiens)
KRM:DKK:LRP5/6 [plasma membrane] (Homo sapiens)
KRM1/2 [plasma membrane] (Homo sapiens)
KRM1 [plasma membrane] (Homo sapiens)
WNT binds to FZD and LRP5/6 (Homo sapiens)
KRM:DKK:LRP5/6 [plasma membrane] (Homo sapiens)
KRM1/2 [plasma membrane] (Homo sapiens)
KRM1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96MU8 KREMEN1
Gene Names
KREMEN1, KREMEN, KRM1
Chain
signal peptide:1-19, chain:20-473
Reference Genes
BioGPS Gene:83999 KREMEN1
COSMIC (genes):KREMEN1 KREMEN1
CTD Gene:83999 KREMEN1
dbSNP Gene:83999 KREMEN1
ENSEMBL:ENSG00000183762 KREMEN1
HGNC:17550 KREMEN1
KEGG:hsa:83999 KREMEN1
Monarch:83999 KREMEN1
NCBI Gene:83999 KREMEN1
OMIM:609898 KREMEN1
UCSC:Q96MU8 KREMEN1
Reference Transcript
RefSeq:NM_001039570.2 KREMEN1
RefSeq:NM_032045.4 KREMEN1
Other Identifiers
11723729_at
11723730_at
11737679_at
16928716
224534_PM_at
224534_at
227250_PM_at
227250_at
234843_PM_s_at
234843_s_at
235370_PM_at
235370_at
243029_PM_at
243029_at
3941794
3941795
3941804
3941807
3941815
3941818
3941820
3941821
3941822
3941823
3941824
3941825
3941826
3941827
3941828
3941829
3941831
3941832
3941833
3941834
3941835
3941836
3941840
3941841
3941843
3941845
43993_at
47771_at
76517_at
77873_at
8072170
83999
A_14_P110852
A_23_P211401
A_23_P68851
A_33_P3262431
GE83303
GE88031
GO:0005515
GO:0005886
GO:0006915
GO:0007154
GO:0012501
GO:0016020
GO:0016055
GO:0030279
GO:0043025
GO:0048681
GO:0048856
GO:0060173
GO:0060828
GO:0090090
HMNXSV003036819
HMNXSV003038362
Hs.26942.0.A1_3p_at
Hs.272274.0.S1_3p_s_at
Hs.310729.0.S1_3p_at
Hs.310729.0.S1_3p_x_at
Hs.62654.0.A1_3p_at
ILMN_1700994
ILMN_1748007
ILMN_1772697
ILMN_1788936
PH_hs_0023147
PH_hs_0036073
TC22000191.hg
g13591619_3p_at
Participates
as a candidate of
KRM1/2 [plasma membrane] (Homo sapiens)
Other forms of this molecule
KRM1 [early endosome membrane]
Inferred To
KREMEN1 [plasma membrane]
(Bos taurus)
KREMEN1 [plasma membrane]
(Canis familiaris)
KREMEN1 [plasma membrane]
(Sus scrofa)
kremen1 [plasma membrane]
(Xenopus tropicalis)
Kremen1 [plasma membrane]
(Mus musculus)
Kremen1 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_114434.3
,
NP_001034659.2
ENSEMBL
ENSP00000385431
,
ENST00000327813
,
ENST00000407188
,
ENSP00000383189
,
ENST00000400335
,
ENSP00000331242
OpenTargets
ENSG00000183762
HPA
ENSG00000183762-KREMEN1
PRO
Q96MU8
Pharos - Targets
Q96MU8
GlyGen
Q96MU8
PDB
5FWS
,
7BZT
,
5FWU
,
7BZU
,
5FWT
,
5FWW
,
5FWV
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