Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
SNAP23 [plasma membrane]
Stable Identifier
R-HSA-376345
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Synaptosomal-associated protein 23, SNP23_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q8IUH5 ZDH17
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Translocation of SLC2A4 (GLUT4) to the plasma membrane (Homo sapiens)
SLC2A4 (GLUT4) vesicle fuses with the plasma membrane (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Vamp2 associated secretory vesicle to plasma membrane transport (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
Vamp7 associated Lysosome to Plasma membrane transport (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
Vamp8 associated secretory vesicle to plasma membrane transport (Homo sapiens)
SNAP23 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00161 SNAP23
Gene Names
SNAP23
Chain
chain:1-211
Reference Genes
BioGPS Gene:8773 SNAP23
COSMIC (genes):SNAP23 SNAP23
CTD Gene:8773 SNAP23
dbSNP Gene:8773 SNAP23
ENSEMBL:ENSG00000092531 SNAP23
ENSEMBL_homo_sapiens_GENE:ENSG00000092531.10 SNAP23
HGNC:11131 SNAP23
KEGG Gene (Homo sapiens):8773 SNAP23
Monarch:8773 SNAP23
NCBI Gene:8773 SNAP23
OMIM:602534 SNAP23
UCSC:O00161 SNAP23
Reference Transcript
RefSeq:NM_003825.3 SNAP23
RefSeq:NM_130798.2 SNAP23
RefSeq:XM_017022694.1 SNAP23
Other Identifiers
11739173_a_at
11739174_x_at
11741581_s_at
11753568_x_at
11757831_x_at
16800095
209130_PM_at
209130_at
209131_PM_s_at
209131_s_at
214544_PM_s_at
214544_s_at
32178_r_at
32179_s_at
3591008
3591013
3591014
3591015
3591019
3591020
3591027
3591028
3591031
3591032
3591033
3591034
46749_i_at
7983111
8773
A_23_P206177
A_33_P3305974
GE81326
GO:0002376
GO:0002553
GO:0005484
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005764
GO:0005773
GO:0005886
GO:0005912
GO:0005925
GO:0006887
GO:0006892
GO:0006903
GO:0006954
GO:0015031
GO:0016020
GO:0016082
GO:0016192
GO:0017075
GO:0019905
GO:0023052
GO:0030670
GO:0031201
GO:0031410
GO:0031629
GO:0035579
GO:0042581
GO:0042582
GO:0043005
GO:0043226
GO:0045202
GO:0060090
GO:0061024
GO:0061025
GO:0065003
GO:0070032
GO:0070062
GO:0070821
GO:0098793
HMNXSV003029186
ILMN_1687519
ILMN_1748911
PH_hs_0023005
TC15000320.hg
U55936_at
g13277555_3p_at
g1374812_3p_a_at
Participates
as an output of
Vamp8 associated secretory vesicle to plasma membrane transport (Homo sapiens)
Vamp2 associated secretory vesicle to plasma membrane transport (Homo sapiens)
Vamp7 associated Lysosome to Plasma membrane transport (Homo sapiens)
as an input of
Vamp8 associated secretory vesicle to plasma membrane transport (Homo sapiens)
Vamp2 associated secretory vesicle to plasma membrane transport (Homo sapiens)
Vamp7 associated Lysosome to Plasma membrane transport (Homo sapiens)
SLC2A4 (GLUT4) vesicle fuses with the plasma membrane (Homo sapiens)
as a component of
Vamp8:SNAP23:Syn4 Secretory granule docking and fusion complex [plasma membrane] (Homo sapiens)
Vamp2:SNAP23:Syn4 Secretory granule docking and fusion complex [plasma membrane] (Homo sapiens)
Vamp7:SNAP23:Syn4 Plasma membrane vesicle docking and fusion complex [plasma membrane] (Homo sapiens)
VAMP2:STX4:SNAP23 [plasma membrane] (Homo sapiens)
as a candidate of
RHOA plasma membrane effectors [cytosol] (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
RHOF effectors [cytosol] (Homo sapiens)
RHOB effectors (plasma membrane) [cytosol] (Homo sapiens)
RHOJ effectors [cytosol] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
as a member of
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
SNAP23 [phagocytic vesicle membrane]
p-S95-SNAP23 [phagocytic vesicle membrane]
SNAP23 [tertiary granule membrane]
SNAP23 [specific granule membrane]
Inferred To
SEC9 [plasma membrane]
(Saccharomyces cerevisiae)
snap23 [plasma membrane]
(Xenopus tropicalis)
cspA [plasma membrane]
(Dictyostelium discoideum)
Snap23 [plasma membrane]
(Mus musculus)
Snap23 [plasma membrane]
(Rattus norvegicus)
SPO20 [plasma membrane]
(Saccharomyces cerevisiae)
SNAP23 [plasma membrane]
(Bos taurus)
SNAP23 [plasma membrane]
(Canis familiaris)
SNAP23 [plasma membrane]
(Dictyostelium discoideum)
SNAP23 [plasma membrane]
(Gallus gallus)
SNAP23 [plasma membrane]
(Plasmodium falciparum)
SNAP23 [plasma membrane]
(Sus scrofa)
Snap24 [plasma membrane]
(Drosophila melanogaster)
aex-4 [plasma membrane]
(Caenorhabditis elegans)
Snap25 [plasma membrane]
(Drosophila melanogaster)
ric-4 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SNAP23 [plasma membrane]
(Caenorhabditis elegans)
Homologues of SNAP23 [plasma membrane]
(Dictyostelium discoideum)
Homologues of SNAP23 [plasma membrane]
(Drosophila melanogaster)
Homologues of SNAP23 [plasma membrane]
(Saccharomyces cerevisiae)
sec9 [plasma membrane]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_570710.1
,
NP_003816.2
,
XP_016878183.1
OpenTargets
ENSG00000092531
HPA
ENSG00000092531-SNAP23
GeneCards
O00161
Ensembl
ENSG00000092531
,
ENST00000249647
,
ENSP00000380327
,
ENST00000397138
,
ENSP00000249647
,
ENST00000349777
,
ENSP00000207062
PRO
O00161
Pharos - Targets
O00161
PDB
1NHL
,
3ZUS
Interactors (13)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O75558 STX11
0.871
11
UniProt:P54920 NAPA
1
NAPA [cytosol]
(R-HSA-264469)
0.779
5
UniProt:Q15836 VAMP3
6
VAMP3 [recycling endosome membrane]
(R-HSA-2029063)
VAMP3 [phagocytic vesicle membrane]
(R-HSA-2029013)
VAMP3 [plasma membrane]
(R-HSA-8867599)
VAMP3 [trans-Golgi network membrane]
(R-HSA-6814624)
VAMP3 [transport vesicle]
(R-HSA-6814625)
VAMP3 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869130)
0.669
3
UniProt:Q9H115 NAPB
1
NAPB [cytosol]
(R-HSA-5688553)
0.556
3
UniProt:Q16623 STX1A
5
STX1A [plasma membrane]
(R-HSA-449128)
STX1A(?-288) [plasma membrane]
(R-HSA-5246518)
STX1A(1-?) [cytosol]
(R-HSA-3065964)
STX1A [cytosol]
(R-HSA-9609866)
STX1A [endoplasmic reticulum membrane]
(R-HSA-9609878)
0.553
2
UniProt:Q13277 STX3
1
STX3 [plasma membrane]
(R-HSA-449131)
0.547
2
UniProt:O76038 SEGN
0.547
3
UniProt:O95183 VAMP5
0.527
2
UniProt:Q86Y82 STX12
0.527
4
UniProt:O15400 STX7
0.527
4
UniProt:Q8IUH5 ZDH17
0.508
4
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
7
UniProt:P56962 STX17
1
STX17 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-6807769)
0.471
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text