Reactome | SLC7A3 [plasma membrane]

SLC7A3 [plasma membrane]

Stable Identifier

R-HSA-375779

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Cationic amino acid transporter 3, CAT-3

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8WY07 SLC7A3

Gene Names

SLC7A3, ATRC3, CAT3

Chain

chain:1-619

Reference Genes

BioGPS Gene:84889 SLC7A3

COSMIC (genes):SLC7A3 SLC7A3

CTD Gene:84889 SLC7A3

dbSNP Gene:84889 SLC7A3

ENSEMBL:ENSG00000165349 SLC7A3

HGNC:11061 SLC7A3

KEGG:hsa:84889 SLC7A3

Monarch:84889 SLC7A3

NCBI Gene:84889 SLC7A3

OMIM:300443 SLC7A3

UCSC:Q8WY07 SLC7A3

Reference Transcript

Other Identifiers

11727909_at

17111858

230597_PM_at

230597_at

4011744

4011745

4011747

4011749

4011750

4011752

4011753

4011754

4011755

4011756

4011757

4011758

4011759

4011760

4011761

59554_at

8173414

84889

A_23_P159851

GE61765

GO:0000064

GO:0003013

GO:0005215

GO:0005515

GO:0005886

GO:0006865

GO:0015171

GO:0015174

GO:0015189

GO:0016020

GO:0022857

GO:0055085

GO:0061459

GO:0097638

GO:0097639

GO:0097640

GO:0150104

GO:1903352

GO:1903401

GO:1903826

HMNXSV003050644

Hs.175220.0.A1_3p_at

ILMN_1660730

ILMN_2401457

PH_hs_0010461

TC0X001117.hg

Inferred To

slc7a3 [plasma membrane] (Xenopus tropicalis)

slif [plasma membrane] (Drosophila melanogaster)

tadr [plasma membrane] (Drosophila melanogaster)

Slc7a3 [plasma membrane] (Mus musculus)

Slc7a3 [plasma membrane] (Rattus norvegicus)

ctrC [plasma membrane] (Dictyostelium discoideum)

Dmel\CG7255 [plasma membrane] (Drosophila melanogaster)

Homologues of SLC7A3 [plasma membrane] (Dictyostelium discoideum)

Homologues of SLC7A3 [plasma membrane] (Drosophila melanogaster)

SLC7A3 [plasma membrane] (Bos taurus)

SLC7A3 [plasma membrane] (Dictyostelium discoideum)

SLC7A3 [plasma membrane] (Gallus gallus)

SLC7A3 [plasma membrane] (Sus scrofa)

anon-WO0118547.111 [plasma membrane] (Drosophila melanogaster)

ctrB [plasma membrane] (Dictyostelium discoideum)

SNX12 [plasma membrane] (Canis familiaris)

ctrA [plasma membrane] (Dictyostelium discoideum)

Cross References

Guide to Pharmacology - Targets

893

ENSEMBL

ENSP00000298085, ENST00000374299, ENST00000298085, ENSP00000363417

OpenTargets

ENSG00000165349

HPA

ENSG00000165349-SLC7A3

PRO

Q8WY07

Pharos - Targets

Q8WY07

GlyGen

Q8WY07

HMDB Protein

HMDBP03114

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14973 SLC10A1	1	SLC10A1 [plasma membrane] (R-HSA-194116)	0.556	3
UniProt:Q96Q45-2 TMEM237			0.556	3
UniProt:Q9H8X2 IPPK	2	IPPK [cytosol] (R-HSA-1604598) IPPK [nucleoplasm] (R-HSA-2023949)	0.527	2
UniProt:P34741 SDC2	20	HS(4)-SDC2 [plasma membrane] (R-HSA-2076683) HS(6)-SDC2 [plasma membrane] (R-HSA-2076661) HS(2)-SDC2 [plasma membrane] (R-HSA-2076644) HS(1)-SDC2 [plasma membrane] (R-HSA-2076643) HS(3)-SDC2 [plasma membrane] (R-HSA-2076631) HS(5)-SDC2 [plasma membrane] (R-HSA-2076665) SDC2 [endoplasmic reticulum lumen] (R-HSA-8956741) p-SDC2 [endoplasmic reticulum lumen] (R-HSA-8956945) XylS-SDC2 [Golgi lumen] (R-HSA-2064109) Gal-Xyl-SDC2 [Golgi lumen] (R-HSA-2064132) SDC2 [Golgi lumen] (R-HSA-2054101) Gal-Gal-Xyl-SDC2 [Golgi lumen] (R-HSA-2063988) GlcA-Gal-Gal-Xyl-SDC2 [Golgi lumen] (R-HSA-2063997) HS(3)-SDC2 [Golgi lumen] (R-HSA-2076443) HS(4)-SDC2 [Golgi lumen] (R-HSA-2076356) HS(2)-SDC2 [Golgi lumen] (R-HSA-2076603) HS(1)-SDC2 [Golgi lumen] (R-HSA-2076607) Heparan(4)-SDC2 [Golgi lumen] (R-HSA-2076576) Heparan(3)-SDC2 [Golgi lumen] (R-HSA-2076361) Heparan(2)-SDC2 [Golgi lumen] (R-HSA-2076397)	0.527	2
UniProt:O43505 B4GAT1	1	B4GAT1 [Golgi membrane] (R-HSA-916821)	0.527	2
UniProt:P22732 SLC2A5	2	SLC2A5 [specific granule membrane] (R-HSA-6799571) SLC2A5 [plasma membrane] (R-HSA-189202)	0.527	2
UniProt:Q96P53 WDFY2			0.527	2
UniProt:Q9Y2B1 RXLT1			0.527	2

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