SLC36A1-mediated uptake of glycine, proline, and alanine

Stable Identifier
R-HSA-375417
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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SLC36A1-mediated uptake of glycine, proline, and alanine
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SLC36A1 (PAT1), associated with the plasma membrane, mediates the uptake of glycine, alanine, and proline coupled to the uptake of a proton. Northern blotting experiments indicate gene expression principally in the intestine (Chen et al. 2003).
Literature References
PubMed ID Title Journal Year
12527723 Structure, function and immunolocalization of a proton-coupled amino acid transporter (hPAT1) in the human intestinal cell line Caco-2

Wake, KA, Thwaites, DT, Ganapathy, V, Huang, W, Anderson, CM, Miyauchi, S, Fei, YJ, Chen, Z

J Physiol 2003
Participants
Input
Output
Participates
as an event of
Catalyst Activity

amino acid transmembrane transporter activity of SLC36A1 [plasma membrane]

Physical Entity
SLC36A1 [plasma membrane] (Homo sapiens)
Activity
amino acid transmembrane transporter activity (GO:0015171)
Orthologous Events
SLC36A1-mediated uptake of glycine, proline, and alanine (Bos taurus)
SLC36A1-mediated uptake of glycine, proline, and alanine (Caenorhabditis elegans)
SLC36A1-mediated uptake of glycine, proline, and alanine (Canis familiaris)
SLC36A1-mediated uptake of glycine, proline, and alanine (Dictyostelium discoideum)
SLC36A1-mediated uptake of glycine, proline, and alanine (Drosophila melanogaster)
SLC36A1-mediated uptake of glycine, proline, and alanine (Gallus gallus)
SLC36A1-mediated uptake of glycine, proline, and alanine (Mus musculus)
SLC36A1-mediated uptake of glycine, proline, and alanine (Rattus norvegicus)
SLC36A1-mediated uptake of glycine, proline, and alanine (Saccharomyces cerevisiae)
SLC36A1-mediated uptake of glycine, proline, and alanine (Sus scrofa)
SLC36A1-mediated uptake of glycine, proline, and alanine (Xenopus tropicalis)
Cross References
Rhea
Authored
D'Eustachio, P  (2008-06-03)
Reviewed
Jassal, B  (2008-06-03)
Created
D'Eustachio, P  (2008-08-27)
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