SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol

Stable Identifier
R-HSA-375405
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane, cytosol, extracellular region
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
SLC36A2 (PAT2), associated with the plasma membrane, has been shown in a limited set of tests in vitro to mediate the uptake of glycine and proline coupled to the uptake of a proton (Boll et al. 2003). PAT2 is most abundantly expressed in kidney and muscle.
Literature References
PubMed ID Title Journal Year
12809675 A cluster of proton/amino acid transporter genes in the human and mouse genomes

Boll, M, Foltz, M, Rubio-Aliaga, I, Daniel, H

Genomics 2003
Participants
Input
Output
Participates
as an event of
Catalyst Activity

amino acid transmembrane transporter activity of SLC36A2 [plasma membrane]

Physical Entity
SLC36A2 [plasma membrane] (Homo sapiens)
Activity
amino acid transmembrane transporter activity (GO:0015171)
Orthologous Events
SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Bos taurus)
SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Caenorhabditis elegans)
SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Canis familiaris)
SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Dictyostelium discoideum)
SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Drosophila melanogaster)
SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Gallus gallus)
SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Mus musculus)
SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Rattus norvegicus)
SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Saccharomyces cerevisiae)
SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Sus scrofa)
SLC36A2 cotransports Gly, L-Pro with H+ from extracellular region to cytosol (Xenopus tropicalis)
Cross References
RHEA
Rhea
Authored
D'Eustachio, P  (2008-06-03)
Reviewed
Jassal, B  (2008-06-03)
Created
D'Eustachio, P  (2008-08-27)
Cite Us!