Connexin 36 mediated neuronal gap junction communication

Stable Identifier
R-HSA-375342
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cell junction
ReviewStatus
5/5
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Connexin 36 mediated neuronal gap junction communication
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In this electrical synapse the current generated in the presynaptic cell spreads to the postsynaptic cell through an ion channel composed of two hemi-channels composed of six Connexin 36 proteins each.

Literature References
PubMed ID Title Journal Year
10462698 Structure, chromosomal localization, and brain expression of human Cx36 gene

Mudo, G, Trovato-Salinaro, A, Hurd, YL, Condorelli, DF, Belluardo, N

J Neurosci Res 1999
Participants
Input
Output
Entity On Other Cell
Participates
as an event of
Catalyst Activity

gap junction channel activity of Connexin 36 Gap Junction Complex [plasma membrane]

Physical Entity
Connexin 36 Gap Junction Complex [plasma membrane] (Homo sapiens)
Activity
gap junction channel activity (GO:0005243)
Orthologous Events
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Connexin 36 mediated neuronal gap junction communication (Mus musculus)
Connexin 36 mediated neuronal gap junction communication (Rattus norvegicus)
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Connexin 36 mediated neuronal gap junction communication (Xenopus tropicalis)
Authored
Gillespie, ME  (2009-02-23)
Reviewed
Rush, MG  (2008-01-11)
Created
Gillespie, ME  (2008-08-26)
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