Connexin 62 mediated neuronal gap junction communication

Stable Identifier
R-HSA-375340
Type
Reaction [transition]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Connexin 62 mediated neuronal gap junction communication
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In this electrical synapse the current generated in the presynaptic cell spreads to the postsynaptic cell through an ion channel composed of two hemi-channels composed of six Connexin 62 proteins each.
Literature References
PubMed ID Title Journal Year
12881038 Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues

Söhl, G, Nielsen, PA, Eiberger, J, Willecke, K

Cell Commun Adhes 2003
Participants
Input
Output
Entity On Other Cell
Participates
as an event of
Catalyst Activity

gap junction channel activity of Connexin 62 Gap Junction Complex [plasma membrane]

Physical Entity
Connexin 62 Gap Junction Complex [plasma membrane] (Homo sapiens)
Activity
gap junction channel activity (GO:0005243)
Orthologous Events
Connexin 62 mediated neuronal gap junction communication (Bos taurus)
Connexin 62 mediated neuronal gap junction communication (Canis familiaris)
Connexin 62 mediated neuronal gap junction communication (Danio rerio)
Connexin 62 mediated neuronal gap junction communication (Gallus gallus)
Connexin 62 mediated neuronal gap junction communication (Mus musculus)
Connexin 62 mediated neuronal gap junction communication (Rattus norvegicus)
Connexin 62 mediated neuronal gap junction communication (Sus scrofa)
Connexin 62 mediated neuronal gap junction communication (Xenopus tropicalis)
Authored
Gillespie, ME  (2009-02-23)
Reviewed
Rush, MG  (2008-01-11)
Created
Gillespie, ME  (2008-08-26)
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