Pannexin 1/Pannexin2 mediated neuronal gap junction communication

Stable Identifier
R-HSA-375339
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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In this electrical synapse the current generated in the presynaptic cell spreads to the postsynaptic cell through an ion channel composed of two hemi-channels composed of six Pannexin 1 proteins on one hemi-channel and six Pannexin 2 proteins on the second.

Literature References
PubMed ID Title Journal Year
14597722 Pannexins, a family of gap junction proteins expressed in brain

Bruzzone, R, Hormuzdi, SG, Barbe, MT, Herb, A, Monyer, H

Proc Natl Acad Sci U S A 2003
Participants
Entity On Other Cell
Participant Of
Catalyst Activity
Catalyst Activity
Title
gap junction channel activity of Pannexin 1/Pannexin 2 Gap Junction Complex [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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