Neogenin:Netrin-3 binds CDO complex

Stable Identifier
R-HSA-375141
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Neogenin:Netrin-3 binds CDO complex
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CDO selectively binds to neogenin in a cis fashion and this interaction involves extracellular domains of both proteins. CDO is essential in mediating netrin-3-induced differentiation of myoblasts by neogenin. Neogenin and netrin-3 stimulate myotube formation and enhance myogenic bHLH-and NFAT-dependent transcription.

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Inferred From
Neogenin:Netrin-3 binds CDO complex (Mus musculus)
Authored
Garapati, P V  (2008-08-11)
Reviewed
Krauss, RS  (2010-02-09)
Created
Garapati, P V  (2008-08-11)
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