CDO binds BOC

Stable Identifier
R-HSA-375138
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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CDO and BOC form complexes in a cis fashion via association of both their ectodomains and their intracellular domains. CDO and BOC exert their effects as components of a receptor, in which the role of BOC is primarily extracellular and that of CDO includes intracellular signaling.
Literature References
PubMed ID Title Journal Year
9786951 CDO, a robo-related cell surface protein that mediates myogenic differentiation

Mulieri, PJ, Kang, JS, Sassoon, DA, Miller, C, Krauss, RS

J Cell Biol 1998
11782431 BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation

Mulieri, PJ, Kang, JS, Hu, Y, Taliana, L, Krauss, RS

EMBO J 2002
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