Reactome | CDO binds BOC

CDO binds BOC

Stable Identifier

R-HSA-375138

Type

Reaction [binding]

Species

Homo sapiens

Compartment

plasma membrane

ReviewStatus

5/5

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CDO and BOC form complexes in a cis fashion via association of both their ectodomains and their intracellular domains. CDO and BOC exert their effects as components of a receptor, in which the role of BOC is primarily extracellular and that of CDO includes intracellular signaling.

Literature References

PubMed ID	Title	Journal	Year
9786951	CDO, a robo-related cell surface protein that mediates myogenic differentiation Mulieri, PJ, Kang, JS, Sassoon, DA, Miller, C, Krauss, RS	J Cell Biol	1998
11782431	BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation Mulieri, PJ, Kang, JS, Hu, Y, Taliana, L, Krauss, RS	EMBO J	2002