Basigin binds CD98 complex

Stable Identifier
R-HSA-375131
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Basigin binds CD98 complex
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CD97hc is a multifunctional glycoprotein with a single transmembrane domain, is highly expressed on proliferating cells, and functions as a chaperone for transporters. CD98hc forms disulfide-bonded heterodimers with at least seven different light chains (SLC7A5-11) that serve as amino acid transporters. Covalent cross-linking, mass spectrometric protein identification, and co-immunoprecipitation shows selective CD147 association with CD98hc complex.
Literature References
PubMed ID Title Journal Year
15901826 Metabolic activation-related CD147-CD98 complex

Xu, D, Hemler, ME

Mol Cell Proteomics 2005
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Orthologous Events
Basigin binds CD98 complex (Bos taurus)
Basigin binds CD98 complex (Canis familiaris)
Basigin binds CD98 complex (Drosophila melanogaster)
Basigin binds CD98 complex (Mus musculus)
Basigin binds CD98 complex (Rattus norvegicus)
Basigin binds CD98 complex (Sus scrofa)
Basigin binds CD98 complex (Xenopus tropicalis)
Authored
Garapati, P V  (2008-02-26)
de Bono, B  (2008-02-26)
Reviewed
Trowsdale, J  (2008-02-26)
Created
Garapati, P V  (2008-08-11)
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