Noradrenaline clearance from the synaptic cleft

Stable Identifier
R-HSA-374919
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane, cytosol
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Noradrenaline clearance from the synaptic cleft
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Noradrenaline is cleared from the synaptic cleft by Noaradrenaline uptake transporter. This reaction is carried out by neurons as well as astrocytes.

Literature References
PubMed ID Title Journal Year
9260930 Cloning and characterization of two human polyspecific organic cation transporters

Gorboulev, V, Ulzheimer, JC, Akhoundova, A, Ulzheimer-Teuber, I, Karbach, U, Quester, S, Baumann, C, Lang, F, Busch, AE, Koepsell, H

DNA Cell Biol 1997
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
neurotransmitter transmembrane transporter activity of OCT2 [plasma membrane]
Physical Entity
OCT2 [plasma membrane]
Activity
neurotransmitter transmembrane transporter activity (0005326)
Orthologous Events
Noradrenaline clearance from the synaptic cleft (Bos taurus)
Noradrenaline clearance from the synaptic cleft (Caenorhabditis elegans)
Noradrenaline clearance from the synaptic cleft (Canis familiaris)
Noradrenaline clearance from the synaptic cleft (Danio rerio)
Noradrenaline clearance from the synaptic cleft (Drosophila melanogaster)
Noradrenaline clearance from the synaptic cleft (Gallus gallus)
Noradrenaline clearance from the synaptic cleft (Mus musculus)
Noradrenaline clearance from the synaptic cleft (Plasmodium falciparum)
Noradrenaline clearance from the synaptic cleft (Rattus norvegicus)
Noradrenaline clearance from the synaptic cleft (Xenopus tropicalis)
Authored
Mahajan, SS  (2008-01-14)
Reviewed
Restituito, S  (2008-11-27)
Created
Mahajan, SS  (2008-08-06)