Noradrenaline clearance from the synaptic cleft

Stable Identifier
R-HSA-374919
Type
Reaction
Species
Homo sapiens
Compartment
extracellular region, plasma membrane, cytosol
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Noradrenaline clearance from the synaptic cleft
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Noradrenaline is cleared from the synaptic cleft by Noaradrenaline uptake transporter. This reaction is carried out by neurons as well as astrocytes.

Literature References
PubMed ID Title Journal Year
9260930 Cloning and characterization of two human polyspecific organic cation transporters

Koepsell, H, Ulzheimer, JC, Quester, S, Busch, AE, Akhoundova, A, Lang, F, Baumann, C, Karbach, U, Gorboulev, V, Ulzheimer-Teuber, I

DNA Cell Biol 1997
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
norepinephrine uptake (0051620)
Catalyst Activity

neurotransmitter transmembrane transporter activity of SLC22A1,SLC22A2 [plasma membrane]

Physical Entity
SLC22A1,SLC22A2 [plasma membrane] (Homo sapiens)
Activity
neurotransmitter transmembrane transporter activity (GO:0005326)
Orthologous Events
Noradrenaline clearance from the synaptic cleft (Bos taurus)
Noradrenaline clearance from the synaptic cleft (Caenorhabditis elegans)
Noradrenaline clearance from the synaptic cleft (Canis familiaris)
Noradrenaline clearance from the synaptic cleft (Danio rerio)
Noradrenaline clearance from the synaptic cleft (Drosophila melanogaster)
Noradrenaline clearance from the synaptic cleft (Gallus gallus)
Noradrenaline clearance from the synaptic cleft (Mus musculus)
Noradrenaline clearance from the synaptic cleft (Rattus norvegicus)
Noradrenaline clearance from the synaptic cleft (Sus scrofa)
Authored
Mahajan, SS  (2008-01-14)
Reviewed
Restituito, S  (2008-11-27)
Created
Mahajan, SS  (2008-08-05)
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