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APLN(65-77)
Stable Identifier
R-HSA-374315
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Apelin-13, APEL_HUMAN, APLN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
APLNR:Apelin peptides [plasma membrane] (Homo sapiens)
Apelin peptides [extracellular region] (Homo sapiens)
APLN(65-77) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
APLNR:Apelin peptides [plasma membrane] (Homo sapiens)
Apelin peptides [extracellular region] (Homo sapiens)
APLN(65-77) [extracellular region] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
APLNR:Apelin peptides [plasma membrane] (Homo sapiens)
Apelin peptides [extracellular region] (Homo sapiens)
APLN(65-77) [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
APLNR:Apelin peptides [plasma membrane] (Homo sapiens)
Apelin peptides [extracellular region] (Homo sapiens)
APLN(65-77) [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
APLNR:Apelin peptides [plasma membrane] (Homo sapiens)
Apelin peptides [extracellular region] (Homo sapiens)
APLN(65-77) [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gi [extracellular region] (Homo sapiens)
Apelin peptides [extracellular region] (Homo sapiens)
APLN(65-77) [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Apelin receptor binds to apelin (Homo sapiens)
APLNR:Apelin peptides [plasma membrane] (Homo sapiens)
Apelin peptides [extracellular region] (Homo sapiens)
APLN(65-77) [extracellular region] (Homo sapiens)
Apelin peptides [extracellular region] (Homo sapiens)
APLN(65-77) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9ULZ1 APLN
Gene Names
APLN, APEL
Chain
signal peptide:1-22, propeptide:23-41, peptide:42-77, peptide:47-77, peptide:50-77, peptide:65-77
Reference Genes
BioGPS Gene:8862 APLN
COSMIC (genes):APLN APLN
CTD Gene:8862 APLN
dbSNP Gene:8862 APLN
ENSEMBL:ENSG00000171388 APLN
HGNC:16665 APLN
KEGG Gene (Homo sapiens):hsa:8862 APLN
Monarch:8862 APLN
NCBI Gene:8862 APLN
OMIM:300297 APLN
UCSC:Q9ULZ1 APLN
Reference Transcript
RefSeq:NM_017413.4 APLN
Other Identifiers
0002450059
11724665_at
17114007
222856_at
60846_at
8175016
8862
A_23_P113393
A_23_P147755
A_24_P404822
AAF25815
AAH21104
AB023493
AF179680
AL022162
APLN
APLN-201
BAA84975
BC021104
CAI95697
CCDS48165
ENSG00000171388
ENSP00000391800
ENST00000429967
EntrezGene:8862
GE82161
GE87422
GO:0001664
GO:0002026
GO:0002376
GO:0003013
GO:0003674
GO:0005102
GO:0005179
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0006810
GO:0006955
GO:0007165
GO:0007267
GO:0007595
GO:0007631
GO:0008150
GO:0008283
GO:0008284
GO:0016192
GO:0023052
GO:0031652
GO:0031704
GO:0042327
GO:0042592
GO:0042756
GO:0043576
GO:0045776
GO:0045906
GO:0048471
GO:0048856
GO:0050878
GO:0051461
GO:0051466
GO:0060183
GO:0097755
GO:1904022
HGNC:16665
Hs.303084
Hs.303084.0.S3_3p_at
ILMN_1689353
IPR026155
MIM:300297
NM_017413
NP_059109
PF15360
PH_hs_0015648
TC0X001354.hg
uc004eus.4
UPI0000125C4A
Participant Of
hasMember
Apelin peptides [extracellular region]
Other forms of this molecule
APLN(50-77) [extracellular region]
APLN(42-77) [extracellular region]
APLN(47-77) [extracellular region]
Inferred To
APLN(65-77) [extracellular region] (Bos taurus)
APLN(65-77) [extracellular region] (Mus musculus)
APLN(65-77) [extracellular region] (Rattus norvegicus)
APLN(65-77) [extracellular region] (Sus scrofa)
APLN(65-77) [extracellular region] (Xenopus tropicalis)
Cross References
RefSeq
NP_059109.3
GeneCards
Q9ULZ1
ZINC target
Q9ULZ1
PRO
Q9ULZ1
Orphanet
25434
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