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CXCL4 homotetramer [extracellular region]
Stable Identifier
R-HSA-373835
Type
Complex
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR2:CXCR2 ligands [plasma membrane] (Homo sapiens)
CXCR2 ligands [extracellular region] (Homo sapiens)
CXCL4 homotetramer [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR2:CXCR2 ligands [plasma membrane] (Homo sapiens)
CXCR2 ligands [extracellular region] (Homo sapiens)
CXCL4 homotetramer [extracellular region] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR2:CXCR2 ligands [plasma membrane] (Homo sapiens)
CXCR2 ligands [extracellular region] (Homo sapiens)
CXCL4 homotetramer [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR2:CXCR2 ligands [plasma membrane] (Homo sapiens)
CXCR2 ligands [extracellular region] (Homo sapiens)
CXCL4 homotetramer [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR2:CXCR2 ligands [plasma membrane] (Homo sapiens)
CXCR2 ligands [extracellular region] (Homo sapiens)
CXCL4 homotetramer [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR2:CXCR2 ligands [plasma membrane] (Homo sapiens)
CXCR2 ligands [extracellular region] (Homo sapiens)
CXCL4 homotetramer [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Chemokine receptors bind chemokines (Homo sapiens)
Receptor CXCR2 binds ligands CXCL1 to 7 (Homo sapiens)
CXCR2 ligands [extracellular region] (Homo sapiens)
CXCL4 homotetramer [extracellular region] (Homo sapiens)
CXCR2:CXCR2 ligands [plasma membrane] (Homo sapiens)
CXCR2 ligands [extracellular region] (Homo sapiens)
CXCL4 homotetramer [extracellular region] (Homo sapiens)
Participants
components
x 4
PF4(48-101) [extracellular region]
(Homo sapiens)
Participates
as a member of
CXCR2 ligands [extracellular region] (Homo sapiens)
Inferred To
CXCL4 homotetramer [extracellular region]
(Bos taurus)
CXCL4 homotetramer [extracellular region]
(Mus musculus)
CXCL4 homotetramer [extracellular region]
(Rattus norvegicus)
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