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CXCL16 [extracellular region]
Stable Identifier
R-HSA-373826
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
C-X-C motif chemokine 16, CXL16_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCL16 [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCL16 [extracellular region] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCL16 [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCL16 [extracellular region] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCL16 [extracellular region] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCL16 [extracellular region] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Chemokine receptors bind chemokines (Homo sapiens)
Receptor CXCR6 binds CXCL16 ligand (Homo sapiens)
CXCL16 [extracellular region] (Homo sapiens)
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
CXCL16 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H2A7 CXCL16
Gene Names
CXCL16, SCYB16, SRPSOX, UNQ2759/PRO6714
Chain
signal peptide:1-29, chain:30-254
Reference Genes
BioGPS Gene:58191 CXCL16
COSMIC (genes):CXCL16 CXCL16
CTD Gene:58191 CXCL16
dbSNP Gene:58191 CXCL16
ENSEMBL:ENSG00000161921 CXCL16
HGNC:16642 CXCL16
KEGG:hsa:58191 CXCL16
Monarch:58191 CXCL16
NCBI Gene:58191 CXCL16
OMIM:605398 CXCL16
UCSC:Q9H2A7 CXCL16
Reference Transcript
RefSeq:NM_001100812.1 CXCL16
RefSeq:NM_022059.3 CXCL16
Other Identifiers
11739280_a_at
11756645_x_at
16840113
223454_PM_at
223454_at
3742286
3742287
3742288
3742289
3742290
3742291
3742292
3742293
3742294
3742295
3742296
3742297
44095_at
58191
64682_r_at
8011713
A_23_P38505
A_33_P3351249
GE62978
GE84818
GO:0002376
GO:0005041
GO:0005044
GO:0005125
GO:0005576
GO:0005615
GO:0005886
GO:0006898
GO:0006935
GO:0007165
GO:0008009
GO:0010818
GO:0016020
GO:0016192
GO:0030307
GO:0030335
GO:0034097
GO:0034341
GO:0034612
GO:0038024
GO:0048018
GO:0048247
GO:0048870
GO:0098772
HMNXSV003013210
HMNXSV003036746
ILMN_1728478
PH_hs_0004721
TC17001029.hg
g11139543_3p_at
g11139543_3p_x_at
Participates
as an input of
Receptor CXCR6 binds CXCL16 ligand (Homo sapiens)
as a component of
CXCR6:CXCL16 [plasma membrane] (Homo sapiens)
Inferred To
Homologues of CXCL16 [extracellular region]
(Sus scrofa)
Cxcl16 [extracellular region]
(Mus musculus)
Cxcl16 [extracellular region]
(Rattus norvegicus)
CXCL16 [extracellular region]
(Bos taurus)
CXCL16 [extracellular region]
(Canis familiaris)
CXCL16 [extracellular region]
(Sus scrofa)
Cross References
RefSeq
NP_071342.2
,
NP_001094282.1
ENSEMBL
ENSP00000459592
,
ENSG00000161921
,
ENST00000574412
,
ENSP00000293778
,
ENST00000293778
OpenTargets
ENSG00000161921
GeneCards
CXCL16
HPA
ENSG00000161921-CXCL16
PRO
Q9H2A7
Pharos - Targets
Q9H2A7
GlyGen
Q9H2A7
HMDB Protein
HMDBP02246
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