Neurofascin and NrCAM heterodimerization

Stable Identifier
R-HSA-373730
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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Neurofascin and NrCAM heterodimerization
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Neurofascin and NrCAM proteins undergo heterophilic interaction with one another with their extracellular Ig like domains and promote axon outgrowth.
Literature References
PubMed ID Title Journal Year
8922386 Neurofascin induces neurites by heterophilic interactions with axonal NrCAM while NrCAM requires F11 on the axonal surface to extend neurites

Rathjen, FG, Zacharias, U, Leuschner, R, Volkmer, H

J Cell Biol 1996
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Orthologous Events
Neurofascin and NrCAM heterodimerization (Caenorhabditis elegans)
Neurofascin and NrCAM heterodimerization (Sus scrofa)
Authored
Garapati, P V  (2008-07-30)
Reviewed
Maness, PF  (2010-02-16)
Created
Garapati, P V  (2008-07-16)
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