Neurofascin and NrCAM heterodimerization

Stable Identifier
R-HSA-373730
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Neurofascin and NrCAM proteins undergo heterophilic interaction with one another with their extracellular Ig like domains and promote axon outgrowth.

Literature References
PubMed ID Title Journal Year
8922386 Neurofascin induces neurites by heterophilic interactions with axonal NrCAM while NrCAM requires F11 on the axonal surface to extend neurites

Volkmer, H, Leuschner, R, Zacharias, U, Rathjen, FG

J Cell Biol 1996
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