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CNTN1 [plasma membrane]
Stable Identifier
R-HSA-373622
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Contactin-1/F11/F3, Neural cell surface protein F3
Locations in the PathwayBrowser for interactor UniProt:P23471 PTPRZ1
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
L1CAM interactions (Homo sapiens)
Cis-heterodimerization of L1 and Contactin-1/F3/F11 (Homo sapiens)
CNTN1 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Signaling by NOTCH1 (Homo sapiens)
Activated NOTCH1 Transmits Signal to the Nucleus (Homo sapiens)
Contactin-1 (CNTN1) binds NOTCH1 (Homo sapiens)
CNTN1 [plasma membrane] (Homo sapiens)
Signaling by NOTCH2 (Homo sapiens)
NOTCH2 Activation and Transmission of Signal to the Nucleus (Homo sapiens)
NOTCH2 binds CNTN1 (Homo sapiens)
CNTN1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q12860 CNTN1
Gene Names
CNTN1
Chain
signal peptide:1-20, chain:21-993, propeptide:994-1018
Reference Genes
BioGPS Gene:1272 CNTN1
COSMIC (genes):CNTN1 CNTN1
CTD Gene:1272 CNTN1
dbSNP Gene:1272 CNTN1
ENSEMBL:ENSG00000018236 CNTN1
HGNC:2171 CNTN1
KEGG:hsa:1272 CNTN1
Monarch:1272 CNTN1
NCBI Gene:1272 CNTN1
OMIM:600016 CNTN1
UCSC:Q12860 CNTN1
Reference Transcript
RefSeq:XM_011537926.2 CNTN1
RefSeq:NM_001256064.1 CNTN1
RefSeq:XM_006719241.2 CNTN1
RefSeq:NM_001256063.1 CNTN1
RefSeq:XM_005268651.2 CNTN1
RefSeq:NM_001843.3 CNTN1
RefSeq:XM_017018825.1 CNTN1
RefSeq:NM_175038.2 CNTN1
RefSeq:XM_011537927.2 CNTN1
RefSeq:XM_017018827.1 CNTN1
RefSeq:XM_017018826.1 CNTN1
Other Identifiers
11742057_a_at
11759199_at
11759200_at
11759695_at
11760243_a_at
1272
1554784_PM_at
1554784_at
16750154
211203_PM_s_at
211203_s_at
227202_PM_at
227202_at
227209_PM_at
227209_at
241190_at
31809_at
31810_g_at
3411722
3411723
3411737
3411748
3411749
3411750
3411752
3411755
3411756
3411757
3411758
3411759
3411760
3411762
3411763
3411764
3411765
3411766
3411768
3411770
3411771
3411772
3411774
3411776
3411778
3411779
3411781
3411782
3411784
3411785
3411786
3411787
3411792
3411793
3411794
3411799
63491_r_at
7954899
85766_at
88239_i_at
88240_r_at
A_14_P111973
A_14_P112225
A_23_P204541
A_23_P390700
A_24_P128200
A_33_P3409090
GE60363
GE718210
GO:0005515
GO:0005886
GO:0007155
GO:0007219
GO:0007411
GO:0007420
GO:0007626
GO:0010467
GO:0010628
GO:0010765
GO:0010976
GO:0016020
GO:0021549
GO:0030246
GO:0030424
GO:0031175
GO:0032289
GO:0042552
GO:0042734
GO:0043226
GO:0045202
GO:0045211
GO:0048856
GO:0070062
GO:0098552
GO:0098609
GO:0098631
GO:0098632
GO:0098978
HMNXSV003014797
HMNXSV003016549
Hs.143434.2.A1_3p_at
Hs.143434.2.A2_3p_at
Hs.197082.0.A1_3p_at
Hs2.143434.2.S1_3p_at
ILMN_1661852
ILMN_2400407
PH_hs_0008439
TC12000311.hg
TC12002318.hg
Z21488_at
g469044_3p_a_at
Participates
as a component of
L1:CNTN1 [plasma membrane] (Homo sapiens)
Contactin1:CASPR complex [plasma membrane] (Homo sapiens)
CNTN1:NOTCH2 [plasma membrane] (Homo sapiens)
CNTN1:NOTCH1:DTX [plasma membrane] (Homo sapiens)
as an input of
Cis-heterodimerization of L1 and Contactin-1/F3/F11 (Homo sapiens)
NOTCH2 binds CNTN1 (Homo sapiens)
Contactin-1 (CNTN1) binds NOTCH1 (Homo sapiens)
Cross References
ENSEMBL
ENST00000348761
,
ENSP00000447006
,
ENST00000551295
,
ENSP00000261160
,
ENSP00000325660
,
ENSP00000448004
,
ENST00000547849
,
ENSP00000448653
,
ENST00000347616
,
ENSG00000018236
,
ENST00000547702
OpenTargets
ENSG00000018236
GeneCards
CNTN1
HPA
ENSG00000018236-CNTN1
PRO
Q12860
Pharos - Targets
Q12860
GlyGen
Q12860
Orphanet
CNTN1
PDB
3S97
,
2EE2
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P23471 PTPRZ1
2
C4S-PTPRZ1 [plasma membrane]
(R-HSA-9699799)
PTPRZ1 [plasma membrane]
(R-HSA-374561)
0.611
3
UniProt:Q96PV0 SYNGAP1
1
SYNGAP1 [cytosol]
(R-HSA-5658217)
0.527
5
UniProt:Q9UHC6 CNTP2
0.463
5
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