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CNTN2 [plasma membrane]
Stable Identifier
R-HSA-373618
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Axonin-1, Contactin-2, CNTN2_HUMAN, TAG1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
L1CAM interactions (Homo sapiens)
Cis-heterodimerization of L1 and Axonin-1 (Homo sapiens)
CNTN2 [plasma membrane] (Homo sapiens)
L1:Axonin-1 [plasma membrane] (Homo sapiens)
CNTN2 [plasma membrane] (Homo sapiens)
NrCAM interactions (Homo sapiens)
NrCAM binds axonin-1 (Homo sapiens)
CNTN2 [plasma membrane] (Homo sapiens)
NrCAM:Axonin-1 [plasma membrane] (Homo sapiens)
CNTN2 [plasma membrane] (Homo sapiens)
NCAM signaling for neurite out-growth (Homo sapiens)
NCAM1 interactions (Homo sapiens)
Interaction of NCAM1 with contactin-2 (Homo sapiens)
CNTN2 [plasma membrane] (Homo sapiens)
NCAM1-Contactin-2 [plasma membrane] (Homo sapiens)
CNTN2 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q02246 CNTN2
Gene Names
CNTN2, AXT, TAG1, TAX1
Chain
signal peptide:1-30, chain:31-1012, propeptide:1013-1040
Reference Genes
BioGPS Gene:6900 CNTN2
COSMIC (genes):CNTN2 CNTN2
CTD Gene:6900 CNTN2
dbSNP Gene:6900 CNTN2
ENSEMBL:ENSG00000184144 CNTN2
HGNC:2172 CNTN2
KEGG:hsa:6900 CNTN2
Monarch:6900 CNTN2
NCBI Gene:6900 CNTN2
OMIM:190197 CNTN2
UCSC:Q02246 CNTN2
Reference Transcript
RefSeq:NM_005076.4 CNTN2
RefSeq:NM_001346083.1 CNTN2
Other Identifiers
11726789_a_at
11726790_a_at
11726791_at
16676405
206970_PM_at
206970_at
230045_PM_at
230045_at
2376300
2376301
2376303
2376304
2376305
2376306
2376307
2376308
2376309
2376310
2376311
2376312
2376313
2376314
2376315
2376316
2376317
2376318
2376319
2376320
2376321
2376322
2376323
2376324
2376325
2376326
2376327
2376328
2376329
2376330
2376331
2376332
2376333
2376334
2376335
2376336
2376337
2376338
2376339
2376341
2376342
36276_at
52440_at
52642_r_at
6900
7909064
A_23_P63557
A_24_P114142
A_24_P2901
GE59940
GO:0002021
GO:0002023
GO:0005515
GO:0005886
GO:0007155
GO:0007156
GO:0007411
GO:0030154
GO:0030424
GO:0033268
GO:0034330
GO:0043194
GO:0043209
GO:0044224
GO:0045163
GO:0045202
GO:0045211
GO:0045444
GO:0050808
GO:0061024
GO:0070593
GO:0071205
GO:0071206
GO:0097090
GO:0098552
GO:0098631
GO:0098632
HMNXSV003007746
Hs.31599.0.A1_3p_at
ILMN_1718896
PH_hs_0000377
TC01001705.hg
TC01004966.hg
X67734_at
g4827021_3p_at
p26601
Participates
as a component of
NrCAM:Axonin-1 [plasma membrane] (Homo sapiens)
L1:Axonin-1 [plasma membrane] (Homo sapiens)
NCAM1-Contactin-2 [plasma membrane] (Homo sapiens)
as an input of
NrCAM binds axonin-1 (Homo sapiens)
Cis-heterodimerization of L1 and Axonin-1 (Homo sapiens)
Interaction of NCAM1 with contactin-2 (Homo sapiens)
Cross References
RefSeq
NP_005067.1
,
NP_001333012.1
ENSEMBL
ENST00000331830
,
ENSP00000492495
,
ENSP00000491671
,
ENST00000640326
,
ENSP00000330633
,
ENSP00000492617
,
ENST00000638378
,
ENST00000639302
OpenTargets
ENSG00000184144
HPA
ENSG00000184144-CNTN2
PRO
Q02246
Pharos - Targets
Q02246
GlyGen
Q02246
Orphanet
CNTN2
PDB
2OM5
,
8K53
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05067 APP
20
APP(672-713) [extracellular region]
(R-HSA-879340)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
0.556
3
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.553
2
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