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CCR3 [plasma membrane]
Stable Identifier
R-HSA-373106
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
C-C chemokine receptor type 3, CCR3_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CCL13:CCL2,CCR3 [plasma membrane] (Homo sapiens)
CCR2,CCR3 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
CCR3,4,5:CCL5(24-91) [plasma membrane] (Homo sapiens)
CCR3,4,5 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CCL13:CCL2,CCR3 [plasma membrane] (Homo sapiens)
CCR2,CCR3 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
CCR3,4,5:CCL5(24-91) [plasma membrane] (Homo sapiens)
CCR3,4,5 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CCL13:CCL2,CCR3 [plasma membrane] (Homo sapiens)
CCR2,CCR3 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
CCR3,4,5:CCL5(24-91) [plasma membrane] (Homo sapiens)
CCR3,4,5 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CCL13:CCL2,CCR3 [plasma membrane] (Homo sapiens)
CCR2,CCR3 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
CCR3,4,5:CCL5(24-91) [plasma membrane] (Homo sapiens)
CCR3,4,5 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CCL13:CCL2,CCR3 [plasma membrane] (Homo sapiens)
CCR2,CCR3 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
CCR3,4,5:CCL5(24-91) [plasma membrane] (Homo sapiens)
CCR3,4,5 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
CCL13:CCL2,CCR3 [plasma membrane] (Homo sapiens)
CCR2,CCR3 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
CCR3,4,5:CCL5(24-91) [plasma membrane] (Homo sapiens)
CCR3,4,5 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Chemokine receptors bind chemokines (Homo sapiens)
CCR2, CCR3 bind CCL13 (Homo sapiens)
CCL13:CCL2,CCR3 [plasma membrane] (Homo sapiens)
CCR2,CCR3 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
CCR2,CCR3 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
Receptors CCR3, 4 and 5 bind CCL5 ligand (Homo sapiens)
CCR3,4,5 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
CCR3,4,5:CCL5(24-91) [plasma membrane] (Homo sapiens)
CCR3,4,5 [plasma membrane] (Homo sapiens)
CCR3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51677 CCR3
Gene Names
CCR3, CMKBR3
Chain
chain:1-355
Reference Genes
BioGPS Gene:1232 CCR3
COSMIC (genes):CCR3 CCR3
CTD Gene:1232 CCR3
dbSNP Gene:1232 CCR3
ENSEMBL:ENSG00000183625 CCR3
HGNC:1604 CCR3
KEGG Gene (Homo sapiens):1232 CCR3
Monarch:1232 CCR3
NCBI Gene:1232 CCR3
OMIM:601268 CCR3
UCSC:P51677 CCR3
Reference Transcript
RefSeq:NM_178328.1 CCR3
RefSeq:XM_011533335.2 CCR3
RefSeq:NM_178329.2 CCR3
RefSeq:XM_006712960.3 CCR3
RefSeq:NM_001837.3 CCR3
Other Identifiers
0000060279
105377067
11740646_a_at
11741322_a_at
1232
16940161
208304_at
2620818
2620823
2620824
2620826
2620827
2620828
2620832
2620834
2620835
2620836
2620837
33098_at
8079383
A_23_P250302
A_24_P367473
GE553404
GO:0001938
GO:0002376
GO:0003674
GO:0004930
GO:0004950
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005886
GO:0005887
GO:0006935
GO:0006950
GO:0006954
GO:0006955
GO:0006968
GO:0007155
GO:0007165
GO:0007186
GO:0007188
GO:0007204
GO:0008150
GO:0008283
GO:0009897
GO:0016020
GO:0016021
GO:0016032
GO:0016493
GO:0019722
GO:0019957
GO:0040011
GO:0042592
GO:0044403
GO:0045766
GO:0048646
GO:0048856
GO:0048870
GO:0060326
GO:0070098
HMNXSV003040936
ILMN_1722500
ILMN_1763322
PH_hs_0026576
TC03000254.hg
TC03002320.hg
U51241_at
g4502636_3p_at
Participates
as a member of
CCR3,4,5 [plasma membrane] (Homo sapiens)
CCR2,CCR3 [plasma membrane] (Homo sapiens)
Inferred To
Ccr3 [plasma membrane]
(Mus musculus)
Ccr3 [plasma membrane]
(Rattus norvegicus)
Homologues of CCR3 [plasma membrane]
(Danio rerio)
Homologues of CCR3 [plasma membrane]
(Gallus gallus)
ccr11.1 [plasma membrane]
(Danio rerio)
CCR2 [plasma membrane]
(Gallus gallus)
cabz01093075.1 [plasma membrane]
(Danio rerio)
CCR3 [plasma membrane]
(Bos taurus)
CCR3 [plasma membrane]
(Xenopus tropicalis)
ccr8.1 [plasma membrane]
(Danio rerio)
CCR5 [plasma membrane]
(Gallus gallus)
Cross References
RefSeq
XP_011531637.1
,
XP_006713023.1
,
NP_847898.1
,
NP_847899.1
,
NP_001828.1
Guide to Pharmacology - Targets
60
OpenTargets
ENSG00000183625
ZINC - Substances
CCR3_HUMAN
ZINC - Biogenic
CCR3_HUMAN
ZINC target
P51677
PRO
P51677
GlyGen
P51677
ZINC - Investigational
CCR3_HUMAN
HPA
ENSG00000183625-CCR3
GeneCards
P51677
Ensembl
ENSG00000183625
,
ENST00000395942
,
ENST00000395940
,
ENSP00000379273
,
ENST00000545097
,
ENSP00000441600
,
ENSP00000379271
,
ENSP00000350003
,
ENST00000357422
Pharos - Targets
P51677
ZINC - Predictions - Purchasable
CCR3_HUMAN
HMDB Protein
HMDBP07576
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