These three receptors can all bind the CC chemokine CCL16. CCR1 was the first CC chemokine receptor identified (Neote K et al, 1993) and can bind multiple chemokines. CCR1 is found on blood lymphocytes and monocytes. CCR2 is found on monocytes, B cells, activated memory T cells and basophils (Yamagami S et al, 1994). CCR8 is found mainly in the thymus (Tiffany HL et al, 1997).
Murphy, PM, Locati, M, Tiffany, HL, Combadiere, C, Gao, JL, Modi, W, Pease, J, Bonner, TI, Lautens, LL
Endo, N, Ishii, K, Tokuda, Y, Yamagami, S, Tanaka, H
Mak, JY, Schall, TJ, Horuk, R, DiGregorio, D, Neote, K
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