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ST3GAL3 D370Y [Golgi membrane]
Stable Identifier
R-HSA-3702112
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase, SIAT6_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with glycosaminoglycan metabolism (Homo sapiens)
Defective ST3GAL3 causes MCT12 and EIEE15 (Homo sapiens)
Defective ST3GAL3 does not transfer SA to keratan (Homo sapiens)
ST3GAL3 mutants [Golgi membrane] (Homo sapiens)
ST3GAL3 D370Y [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q11203 ST3GAL3
Gene Names
ST3GAL3, SIAT6
Chain
chain:1-375
Reference Genes
BioGPS Gene:6487 ST3GAL3
COSMIC (genes):ST3GAL3 ST3GAL3
CTD Gene:6487 ST3GAL3
dbSNP Gene:6487 ST3GAL3
ENSEMBL:ENSG00000126091 ST3GAL3
HGNC:10866 ST3GAL3
KEGG:hsa:6487 ST3GAL3
Monarch:6487 ST3GAL3
NCBI Gene:6487 ST3GAL3
OMIM:606494 ST3GAL3
UCSC:Q11203 ST3GAL3
Reference Transcript
RefSeq:NM_001270460.1 ST3GAL3
RefSeq:NM_174966.2 ST3GAL3
RefSeq:NM_174967.2 ST3GAL3
RefSeq:NM_001270463.1 ST3GAL3
RefSeq:NM_001270461.1 ST3GAL3
RefSeq:NM_001270465.1 ST3GAL3
RefSeq:NM_174970.2 ST3GAL3
RefSeq:NM_174971.3 ST3GAL3
RefSeq:NM_174963.3 ST3GAL3
RefSeq:NM_001270459.1 ST3GAL3
RefSeq:NM_001270464.1 ST3GAL3
RefSeq:NM_174964.2 ST3GAL3
RefSeq:NM_174965.2 ST3GAL3
RefSeq:NM_001270466.1 ST3GAL3
RefSeq:NM_006279.3 ST3GAL3
RefSeq:NM_174968.3 ST3GAL3
RefSeq:NM_174969.2 ST3GAL3
RefSeq:NM_001270462.1 ST3GAL3
RefSeq:XM_017002113.1 ST3GAL3
Other Identifiers
11724137_a_at
11750100_a_at
11753490_a_at
11753789_a_at
11753790_x_at
11761809_at
1555171_PM_at
1555171_at
1555181_PM_a_at
1555181_a_at
1555678_PM_at
1555678_at
1555702_3p_a_at
1555702_PM_a_at
1555702_a_at
1555703_3p_at
1555703_PM_at
1555703_at
16663694
225905_PM_s_at
225905_s_at
2333478
2333480
2333482
2333483
2333484
2333488
2333489
2333490
2333501
2333502
2333503
2333506
2333507
2333508
2333512
2333513
2333515
2333516
2333518
2333524
2333525
2333526
2333527
2333528
2333530
2333531
2333536
2333537
2333539
2333541
2333542
2333543
2333544
2333546
2333547
2333548
2333549
2333550
2333551
2333552
2333553
2333554
2333555
2333556
2333558
2333559
2333560
2333561
2333571
2333573
242511_PM_at
242511_at
52958_at
6487
78108_at
7900857
A_14_P104218
A_14_P137034
A_23_P200999
A_24_P268123
A_33_P3405966
GE471092
GE62472
GE677606
GE760100
GO:0000139
GO:0003824
GO:0003836
GO:0005515
GO:0005576
GO:0005794
GO:0005975
GO:0006486
GO:0006629
GO:0006688
GO:0006790
GO:0008118
GO:0008373
GO:0009312
GO:0010706
GO:0016020
GO:0016266
GO:0016740
GO:0016757
GO:0018146
GO:0019082
GO:0032580
GO:0043226
GO:1901135
HMNXSV003034243
HMNXSV003049671
HMNXSV003053911
Hs.132001.0.A1_3p_at
Hs.48793.1.S2_3p_at
Hs2.48793.3.S1_3p_s_at
Hs2.48793.7.S1_3p_s_at
Hs2.48793.8.S1_3p_a_at
Hs2.48793.9.S1_3p_a_at
ILMN_1699472
ILMN_2350315
PH_hs_0003412
Participates
as a member of
ST3GAL3 mutants [Golgi membrane] (Homo sapiens)
Other forms of this molecule
ST3GAL3 [Golgi membrane]
ST3GAL3 A320P [Golgi membrane]
ST3GAL3 A13D [Golgi membrane]
Modified Residues
Name
L-aspartic acid 370 replaced with L-tyrosine
Coordinate
370
PsiMod
L-aspartic acid removal [MOD:01634]
A protein modification that effectively removes or replaces an L-aspartic acid.
L-tyrosine residue
A protein modification that effectively converts a source amino acid residue to L-tyrosine.
Disease
Name
Identifier
Synonyms
developmental disorder of mental health
DOID:0060037
Cross References
RefSeq
NP_777626.1
,
XP_016857602.1
,
NP_777624.1
,
NP_777623.2
,
NP_001257389.1
,
NP_001257388.1
,
NP_001257392.1
,
NP_001257390.1
,
NP_001257391.1
,
NP_001257394.1
,
NP_777629.1
,
NP_777628.2
,
NP_001257395.1
,
NP_001257393.1
,
NP_777631.2
,
NP_777627.1
,
NP_777630.1
,
NP_006270.1
,
NP_777625.1
OpenTargets
ENSG00000126091
ENSEMBL
ENST00000528371
,
ENSP00000355201
,
ENSP00000435621
,
ENSP00000432071
,
ENSP00000434876
,
ENST00000361400
,
ENSP00000437206
,
ENST00000372362
,
ENSP00000361447
,
ENST00000645142
,
ENSP00000439634
,
ENST00000372374
,
ENST00000645165
,
ENST00000644195
,
ENSP00000437293
,
ENSP00000494852
,
ENSP00000361444
,
ENSP00000317192
,
ENSP00000361449
,
ENSP00000495887
,
ENSP00000435018
,
ENSP00000361437
,
ENST00000533997
,
ENST00000531816
,
ENST00000361392
,
ENST00000642934
,
ENSP00000496550
,
ENST00000642949
,
ENSP00000361440
,
ENST00000531451
,
ENST00000530581
,
ENST00000351035
,
ENSP00000316999
,
ENSP00000361442
,
ENSP00000494201
,
ENST00000469715
,
ENST00000490541
,
ENSP00000335633
,
ENST00000533212
,
ENSP00000494146
,
ENST00000372366
,
ENST00000330208
,
ENST00000372365
,
ENSP00000434378
,
ENST00000545417
,
ENSP00000355341
,
ENSP00000435603
,
ENSP00000494857
,
ENSP00000262915
,
ENSP00000495709
,
ENSP00000354748
,
ENSP00000432682
,
ENSP00000431700
,
ENST00000642504
,
ENST00000372372
,
ENST00000361812
,
ENSP00000333494
,
ENST00000531993
,
ENST00000489897
,
ENSP00000493660
,
ENST00000347631
,
ENSP00000361441
,
ENST00000262915
,
ENST00000646971
,
ENST00000335430
,
ENST00000372369
,
ENSP00000330463
,
ENST00000353126
,
ENST00000645640
,
ENST00000372367
HPA
ENSG00000126091-ST3GAL3
PRO
Q11203
Pharos - Targets
Q11203
GlyGen
Q11203
Orphanet
ST3GAL3
HMDB Protein
HMDBP00207
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q86TI2-2 Q86TI22
0.556
3
UniProt:Q8N7X4 MAGB6
0.556
3
UniProt:P50453 SPB9
0.499
2
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