Superoxide and nitric oxide react to form peroxynitrite in mitochondria

Stable Identifier
R-HSA-3697855
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
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Superoxide and nitric oxide react to form peroxynitrite in mitochondria
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Superoxide and nitric oxide react to form peroxynitrite within mitochondria (Huie and Padmaja 1993, Packer et al. 1996, reviewed in Radi et al. 2002).

Literature References
PubMed ID Title Journal Year
12446202 Peroxynitrite reactions and formation in mitochondria

Radi, R, Cassina, A, Hodara, R, Quijano, C, Castro, L

Free Radic. Biol. Med. 2002
8396550 The reaction of no with superoxide

Huie, RE, Padmaja, S

Free Radic. Res. Commun. 1993
20194496 Peroxynitrite is the major species formed from different flux ratios of co-generated nitric oxide and superoxide: direct reaction with boronate-based fluorescent probe

Zielonka, J, Sikora, A, Joseph, J, Kalyanaraman, B

J. Biol. Chem. 2010
8908362 Superoxide production by mitochondria in the presence of nitric oxide forms peroxynitrite

Packer, MA, Porteous, CM, Murphy, MP

Biochem. Mol. Biol. Int. 1996
Participants
Input
Output
Participant Of
hasEvent
Cross References
Rhea
Authored
May, B  (2013-06-09)
Reviewed
Kavdia, M  (2013-11-01)
Created
May, B  (2013-06-09)