ATP7A transfers Cu from ATOX1 to SOD3

Stable Identifier
R-HSA-3697838
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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As inferred from mouse, ATP7A (Menke's ATPase, MNK) transports copper from ATOX in the cytosol to SOD3 in the lumen of the trans golgi network. ATP7A and SOD3 directly interact. Mutations in ATP7A cause Menke's disease, a neurodegenerative condition.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
copper transmembrane transporter activity, phosphorylative mechanism of ATP7A [trans-Golgi network membrane]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created