Reactome | MBIP [nucleoplasm]

MBIP [nucleoplasm]

Stable Identifier

R-HSA-3662291

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

MAP3K12-binding inhibitory protein 1, MBIP1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q96ES7 SGF29

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External Reference Information

External Reference

UniProt:Q9NS73 MBIP

Gene Names

MBIP, BM-015

Chain

chain:1-344

Reference Genes

BioGPS Gene:51562 MBIP

COSMIC (genes):MBIP MBIP

CTD Gene:51562 MBIP

dbSNP Gene:51562 MBIP

ENSEMBL:ENSG00000151332 MBIP

HGNC:20427 MBIP

KEGG:hsa:51562 MBIP

Monarch:51562 MBIP

NCBI Gene:51562 MBIP

OMIM:609431 MBIP

UCSC:Q9NS73 MBIP

Reference Transcript

Participates

as a component of

as an input of

Inferred To

MBIP [nucleoplasm] (Bos taurus)

MBIP [nucleoplasm] (Canis familiaris)

MBIP [nucleoplasm] (Gallus gallus)

Mbip [nucleoplasm] (Mus musculus)

Mbip [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001138363.1, NP_001295039.1, NP_057670.2

ENSEMBL

ENSG00000151332, ENSP00000399718, ENST00000318473, ENSP00000324444, ENST00000416007, ENSP00000352517, ENST00000359527

OpenTargets

ENSG00000151332

HPA

ENSG00000151332-MBIP

GeneCards

MBIP

PRO

Q9NS73

Pharos - Targets

Q9NS73

GlyGen

Q9NS73

Interactors (24)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.884	9
UniProt:Q9H8E8 KAT14	1	KAT14 [nucleoplasm] (R-HSA-3301917)	0.861	10
UniProt:Q96ES7 SGF29	1	SGF29 [nucleoplasm] (R-HSA-3662279)	0.725	7
UniProt:Q8N3L3 TXLNB			0.666	4
UniProt:Q13136 PPFIA1	1	PPFIA1 [cytosol] (R-HSA-383377)	0.621	3
UniProt:Q9NS73 MBIP	1	MBIP [nucleoplasm] (R-HSA-3662291)	0.621	3
UniProt:P51116 FXR2			0.621	3
UniProt:Q9H8W4 PKHF2			0.621	3
UniProt:Q96HL7 Q96HL7			0.621	3
UniProt:P00533 EGFR	20	p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541) p-6Y-EGFR A289V [plasma membrane] (R-HSA-1996334)	0.618	3
UniProt:Q06411 SP382			0.556	3
UniProt:Q02821	2	SRP1 [cytosol] (R-SCE-180612) SRP1 [cytosol] (R-SCE-9734672)	0.556	3
UniProt:Q92831 KAT2B	1	KAT2B [nucleoplasm] (R-HSA-352430)	0.527	3
UniProt:O75528 TADA3	1	TADA3 [nucleoplasm] (R-HSA-3322966)	0.527	4
UniProt:Q96S44 TP53RK	1	TP53RK [nucleoplasm] (R-HSA-6784489)	0.527	3
UniProt:Q92830 KAT2A	1	KAT2A [nucleoplasm] (R-HSA-3006516)	0.527	4
UniProt:Q9ULM3 YEATS2	1	YEATS2 [nucleoplasm] (R-HSA-3321976)	0.527	4
UniProt:O75478 TADA2A	1	TADA2A [nucleoplasm] (R-HSA-3662284)	0.527	4
UniProt:Q9Y3C4 TPRKB	1	TPRKB [nucleoplasm] (R-HSA-6784505)	0.527	3
UniProt:Q9NPF4 OSGEP	1	OSGEP [nucleoplasm] (R-HSA-6784522)	0.527	3
UniProt:Q8IYH5 ZZZ3	1	ZZZ3 [nucleoplasm] (R-HSA-3662283)	0.527	4
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.488	2
UniProt:P48059 LIMS1	1	LIMS1 [cytosol] (R-HSA-432859)	0.488	2
UniProt:Q8N381 Q8N381			0.488	2

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