Reactome | MBIP [nucleoplasm]

MBIP [nucleoplasm]

Stable Identifier

R-HSA-3662291

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

MAP3K12-binding inhibitory protein 1, MBIP1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q02821

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External Reference Information

External Reference

UniProt:Q9NS73 MBIP

Gene Names

MBIP, BM-015

Chain

chain:1-344

Reference Genes

BioGPS Gene:51562 MBIP

COSMIC (genes):MBIP MBIP

CTD Gene:51562 MBIP

dbSNP Gene:51562 MBIP

ENSEMBL:ENSG00000151332 MBIP

ENSEMBL_homo_sapiens_GENE:ENSG00000151332.20 MBIP

HGNC:20427 MBIP

KEGG Gene (Homo sapiens):51562 MBIP

Monarch:51562 MBIP

NCBI Gene:51562 MBIP

OMIM:609431 MBIP

UCSC:Q9NS73 MBIP

Reference Transcript

Other Identifiers

11724531_x_at

11763698_x_at

16792101

218411_PM_s_at

218411_s_at

3561329

3561330

3561338

3561341

3561342

3561343

3561348

3561349

3561350

3561351

3561356

3561357

3561358

51562

54691_at

7978666

A_23_P2922

A_33_P3288569

GE54968

GO:0000122

GO:0004860

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005730

GO:0005737

GO:0005829

GO:0005856

GO:0006351

GO:0006355

GO:0006357

GO:0010628

GO:0023052

GO:0036211

GO:0042802

GO:0043226

GO:0045995

GO:0046330

GO:0048856

GO:0051302

GO:0051726

GO:0072686

GO:0090043

GO:0098772

GO:0140672

HMNXSV003006749

HMNXSV003010057

ILMN_1664323

ILMN_2106818

PH_hs_0024077

TC14001046.hg

g7706610_3p_a_at

Participates

as a component of

as an input of

Inferred To

MBIP [nucleoplasm] (Bos taurus)

MBIP [nucleoplasm] (Canis familiaris)

MBIP [nucleoplasm] (Gallus gallus)

Mbip [nucleoplasm] (Mus musculus)

Mbip [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_057670.2, NP_001295039.1, NP_001138363.1

OpenTargets

ENSG00000151332

HPA

ENSG00000151332-MBIP

GeneCards

Q9NS73

Ensembl

ENSP00000352517, ENSG00000151332, ENSP00000324444, ENSP00000399718, ENST00000359527, ENST00000318473, ENST00000416007

PRO

Q9NS73

Pharos - Targets

Q9NS73

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.847	8
UniProt:Q9H8E8 KAT14	1	KAT14 [nucleoplasm] (R-HSA-3301917)	0.818	9
UniProt:Q8N3L3 TXLNB			0.666	4
UniProt:Q96ES7 SGF29	1	SGF29 [nucleoplasm] (R-HSA-3662279)	0.643	6
UniProt:Q13136 PPFIA1	1	PPFIA1 [cytosol] (R-HSA-383377)	0.621	3
UniProt:Q9NS73 MBIP	1	MBIP [nucleoplasm] (R-HSA-3662291)	0.621	3
UniProt:P51116 FXR2			0.621	3
UniProt:Q9H8W4 PKHF2			0.621	3
UniProt:Q96HL7 Q96HL7			0.621	3
UniProt:Q06411 SP382			0.556	3
UniProt:Q02821	2	SRP1 [cytosol] (R-SCE-180612) SRP1 [cytosol] (R-SCE-9734672)	0.556	3
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.508	2
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.488	2
UniProt:P48059 LIMS1	1	LIMS1 [cytosol] (R-HSA-432859)	0.488	2
UniProt:Q8N381 Q8N381			0.488	2

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