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USP22 [nucleoplasm]
Stable Identifier
R-HSA-3662288
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Ubiquitin carboxyl-terminal hydrolase 22 ecNumber3.4.19.12/ecNumber, UBP22_HUMAN
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HATs acetylate histones (Homo sapiens)
KAT2 complexes acetylate histone H3 (Homo sapiens)
KAT2A,B complexes [nucleoplasm] (Homo sapiens)
STAGA complex [nucleoplasm] (Homo sapiens)
USP22 [nucleoplasm] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
USP3, SAGA complex [nucleoplasm] (Homo sapiens)
SAGA [nucleoplasm] (Homo sapiens)
USP22 [nucleoplasm] (Homo sapiens)
USP3,SAGA:Histone H2A,Histone H2B [nucleoplasm] (Homo sapiens)
USP3, SAGA complex [nucleoplasm] (Homo sapiens)
SAGA [nucleoplasm] (Homo sapiens)
USP22 [nucleoplasm] (Homo sapiens)
USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
USP3, SAGA complex [nucleoplasm] (Homo sapiens)
SAGA [nucleoplasm] (Homo sapiens)
USP22 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UPT9 USP22
Gene Names
USP22, KIAA1063, USP3L
Chain
chain:1-525
Reference Genes
BioGPS Gene:23326 USP22
COSMIC (genes):USP22 USP22
CTD Gene:23326 USP22
dbSNP Gene:23326 USP22
ENSEMBL:ENSG00000124422 USP22
ENSEMBL_homo_sapiens_GENE:ENSG00000124422.12 USP22
HGNC:12621 USP22
KEGG Gene (Homo sapiens):23326 USP22
Monarch:23326 USP22
NCBI Gene:23326 USP22
OMIM:612116 USP22
UCSC:Q9UPT9 USP22
Reference Transcript
RefSeq:NM_015276.1 USP22
Other Identifiers
11739017_at
11739018_a_at
16650479
16842452
18671547
18671548
18671551
18671552
18671553
18671554
18671555
18671556
18671557
18671558
18671559
18671560
18671561
200083_PM_at
200083_at
23326
3749506
3749516
3749518
3749520
3749522
3749524
3749526
3749528
3749530
3749532
3749534
3749536
3749538
3749540
3749554
3749562
3749580
3749586
3749602
3749612
3749626
3749642
3749658
3749682
3749718
3749752
3749754
39866_at
7892565
7892620
7892694
7892788
7892837
7893467
7893594
7893690
7893752
7894341
7894546
7894873
7894946
7895069
7895331
7895427
7895913
7896167
7896178
7896191
8013486
A_23_P207068
A_23_P422540
GE79719
GO:0000124
GO:0000278
GO:0003713
GO:0003824
GO:0004843
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0006281
GO:0006282
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006357
GO:0006508
GO:0006807
GO:0007049
GO:0008233
GO:0008234
GO:0008270
GO:0009792
GO:0010485
GO:0016579
GO:0016740
GO:0016787
GO:0019899
GO:0030374
GO:0033276
GO:0036211
GO:0043170
GO:0043226
GO:0043484
GO:0044238
GO:0045893
GO:0045931
GO:0046872
GO:0048856
GO:0140096
GO:0140110
GO:0140936
GO:0140950
HMNXSV003041356
Hs.12064.0.S1_3p_at
ILMN_1666609
PH_hs_0001131
TC17001263.hg
Participates
as a component of
SAGA [nucleoplasm] (Homo sapiens)
STAGA complex [nucleoplasm] (Homo sapiens)
Inferred To
Ghost homologue of USP22 [nucleoplasm]
(Schizosaccharomyces pombe)
Ghost homologue of USP22 [nucleoplasm]
(Sus scrofa)
usp22 [nucleoplasm]
(Xenopus tropicalis)
USP22 [nucleoplasm]
(Bos taurus)
USP22 [nucleoplasm]
(Canis familiaris)
USP22 [nucleoplasm]
(Danio rerio)
USP22 [nucleoplasm]
(Dictyostelium discoideum)
USP22 [nucleoplasm]
(Drosophila melanogaster)
USP22 [nucleoplasm]
(Mus musculus)
USP22 [nucleoplasm]
(Saccharomyces cerevisiae)
Usp22 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_056091.1
OpenTargets
ENSG00000124422
GeneCards
Q9UPT9
HPA
ENSG00000124422-USP22
Ensembl
ENSP00000440950
,
ENSP00000261497
,
ENSG00000124422
,
ENST00000261497
,
ENST00000537526
PRO
Q9UPT9
Pharos - Targets
Q9UPT9
HMDB Protein
HMDBP10115
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NRN7 AASDHPPT
1
AASDHPPT [cytosol]
(R-HSA-199235)
0.675
6
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