Reactome | CHST6 L276P [Golgi membrane]

CHST6 L276P [Golgi membrane]

Stable Identifier

R-HSA-3656477

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Carbohydrate sulfotransferase 6, CHST6_HUMAN

Icon

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9GZX3 CHST6

Gene Names

CHST6

Chain

chain:1-395

Reference Genes

BioGPS Gene:4166 CHST6

COSMIC (genes):CHST6 CHST6

CTD Gene:4166 CHST6

dbSNP Gene:4166 CHST6

ENSEMBL:ENSG00000183196 CHST6

HGNC:6938 CHST6

KEGG:hsa:4166 CHST6

Monarch:4166 CHST6

NCBI Gene:4166 CHST6

OMIM:605294 CHST6

UCSC:Q9GZX3 CHST6

Reference Transcript

Other Identifiers

11735477_a_at

11735478_a_at

16828468

16828471

223786_PM_at

223786_at

3699610

3699617

3699618

3699619

3699620

3699621

3699622

3699623

3699624

3699625

3699626

3699627

3699629

4166

71951_at

8002882

83762_at

A_33_P3366903

GE80585

GO:0000139

GO:0001517

GO:0003824

GO:0005794

GO:0005802

GO:0005975

GO:0006044

GO:0006790

GO:0008146

GO:0016020

GO:0016740

GO:0018146

GO:0043226

GO:0045130

GO:1901135

HMNXSV003024784

HMNXSV003049014

ILMN_1670881

PH_hs_0031900

TC16001281.hg

TC16001963.hg

g12060803_3p_at

Participates

as a member of

CHST6 mutants [Golgi membrane] (Homo sapiens)

Other forms of this molecule

CHST6 [Golgi membrane]

CHST6 C102G [Golgi membrane]

CHST6 L200R [Golgi membrane]

CHST6 D203E [Golgi membrane]

CHST6 E274K [Golgi membrane]

CHST6 Y110C [Golgi membrane]

CHST6 K174R [Golgi membrane]

CHST6 R211W [Golgi membrane]

Modified Residues

Name

L-leucine 276 replaced with L-proline

Coordinate

276

PsiMod

L-leucine removal [MOD:01641]

A protein modification that effectively removes or replaces an L-leucine.

L-proline residue [MOD:00024]

A protein modification that effectively converts a source amino acid residue to L-proline.

Disease

Name	Identifier	Synonyms
macular corneal dystrophy	DOID:2565	Macular Corneal Dystrophy, Macular corneal dystrophy (disorder)

Cross References

OpenTargets

ENSG00000183196

ENSEMBL

ENSP00000496806, ENSP00000328983, ENST00000390664, ENST00000332272, ENSP00000497635, ENST00000649824, ENST00000649341, ENSP00000375079

IntEnz

2.8.2.21

HPA

ENSG00000183196-CHST6

PRO

Q9GZX3

Pharos - Targets

Q9GZX3

Orphanet

CHST6

GlyGen

Q9GZX3

HMDB Protein

HMDBP02328

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8NCG5 CHST4	1	CHST4 [Golgi membrane] (R-HSA-6786006)	0.527	2
UniProt:P27824 CANX	2	CANX [endoplasmic reticulum lumen] (R-HSA-195906) CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091)	0.527	2
UniProt:Q9UBS3 DNAJB9	1	DNAJB9 [endoplasmic reticulum membrane] (R-HSA-381010)	0.527	2

Cite Us!