TGFBR2 MSI frameshift mutants [cytosol]

Stable Identifier
R-HSA-3642198
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
cytosol
Synonyms
TGFBR2 microsatellite instability frameshift mutants, TGFBR2 BAT-RII Mutants
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Literature References
PubMed ID Title Journal Year
7665626 Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells

Sun, L, Willson, JK, Myeroff, L, Gentry, LE, Wang, J, Yang, J, Wang, X, Liang, J, Markowitz, S, Zborowska, E

J. Biol. Chem. 1995
7761852 Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

Fan, RS, Sun, L, Vogelstein, B, Myeroff, L, Wang, J, Kinzler, KW, Parsons, R, Markowitz, S, Zborowska, E, Lutterbaugh, J

Science 1995
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Disease
Name Identifier Synonyms
large intestine cancer DOID:5672 malignant Colorectal tumor, malignant neoplasm of large intestine, NOS, malignant tumor of large intestine (disorder), malignant neoplasm of colon with rectum, malignant neoplasm of large intestine NOS
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
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