SLC38A1 (ATA1)-mediated uptake of neutral amino acids

Stable Identifier
R-HSA-352119
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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SLC38A1 (ATA1), associated with the plasma membrane, mediates the uptake of neutral amino acids, especially alanine, asparagine, glutamine, methionine, and serine in a sodium ion-dependent transport process. Northern blotting experiments indicate gene expression in placenta and heart, and at lower levels in other tissues including brain, lung, skeletal muscle, spleen, stomach and testis, but not kidney or intestine (Wang et al. 2000).

Literature References
PubMed ID Title Journal Year
10891391 Cloning and functional expression of ATA1, a subtype of amino acid transporter A, from human placenta

Wang, H, Huang, W, Sugawara, M, Devoe, LD, Leibach, FH, Prasad, PD, Ganapathy, V

Biochem Biophys Res Commun 2000
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
amino acid transmembrane transporter activity of SLC38A1 [plasma membrane]
Physical Entity
Activity
Orthologous Events
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