SLC43A2 (LAT4)-mediated uptake of large neutral amino acids

Stable Identifier
R-HSA-352107
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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SLC43A2 (LAT4), associated with the plasma membrane, mediates the uptake of isoleucine, leucine, methionine, phenylalanine, and valine in a biphasic and sodium ion-independent transport process. Northern blotting and in situ hybridization experiments indicate gene expression in kidney and intestine (Bodoy et al. 2005).

Literature References
PubMed ID Title Journal Year
15659399 Identification of LAT4, a novel amino acid transporter with system L activity

Bodoy, S, Martin, L, Zorzano, A, Palacin, M, Estévez, R, Bertran, J

J Biol Chem 2005
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
amino acid transmembrane transporter activity of SLC43A2 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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