Reactome | SLC6A15 [plasma membrane]

SLC6A15 [plasma membrane]

Stable Identifier

R-HSA-352060

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser for interactor UniProt:Q8TBA6 GOLGA5

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External Reference Information

External Reference

UniProt:Q9H2J7 SLC6A15

Gene Names

SLC6A15, B0AT2, NTT73, SBAT1

Chain

chain:1-730

Reference Genes

BioGPS Gene:55117 SLC6A15

COSMIC (genes):SLC6A15 SLC6A15

CTD Gene:55117 SLC6A15

dbSNP Gene:55117 SLC6A15

ENSEMBL:ENSG00000072041 SLC6A15

ENSEMBL_homo_sapiens_GENE:ENSG00000072041.18 SLC6A15

HGNC:13621 SLC6A15

KEGG Gene (Homo sapiens):55117 SLC6A15

Monarch:55117 SLC6A15

NCBI Gene:55117 SLC6A15

OMIM:607971 SLC6A15

UCSC:Q9H2J7 SLC6A15

Reference Transcript

Other Identifiers

11715329_at

11742436_at

16768105

206376_PM_at

206376_at

232263_PM_at

232263_at

239352_PM_at

239352_at

240419_PM_at

240419_at

3464277

3464278

3464279

3464280

3464281

3464282

3464284

3464285

3464286

3464287

3464289

3464290

3464291

3464292

3464293

3464294

3464295

3464296

3464297

3464298

3464303

3464307

3464308

3464309

3464310

36318_at

46844_r_at

54256_at

55117

7965206

A_23_P13725

A_23_P356598

A_24_P109838

A_24_P307653

A_33_P3392320

GE534961

GE55714

GE836371

GO:0003333

GO:0005215

GO:0005295

GO:0005298

GO:0005326

GO:0005515

GO:0005886

GO:0006811

GO:0006814

GO:0006836

GO:0006865

GO:0015171

GO:0015293

GO:0015657

GO:0015804

GO:0015820

GO:0015824

GO:0016020

GO:0022857

GO:0035725

GO:0055085

GO:0071702

GO:0071705

GO:1903825

HMNXSV003021851

HMNXSV003023014

Hs.288691.0.S1_3p_at

Hs.42373.0.A1_3p_at

Hs.47650.0.A1_3p_at

ILMN_1659166

ILMN_1810533

ILMN_2291083

PH_hs_0003225

PH_hs_0031199

TC12001783.hg

g8922349_3p_at

Inferred To

slc6a15 [plasma membrane] (Danio rerio)

slc6a15 [plasma membrane] (Xenopus tropicalis)

Homologues of SLC6A15 [plasma membrane] (Drosophila melanogaster)

Homologues of SLC6A15 [plasma membrane] (Plasmodium falciparum)

SLC6A15 [plasma membrane] (Bos taurus)

SLC6A15 [plasma membrane] (Canis familiaris)

SLC6A15 [plasma membrane] (Gallus gallus)

SLC6A15 [plasma membrane] (Plasmodium falciparum)

SLC6A15 [plasma membrane] (Sus scrofa)

Dmel\CG10804 [plasma membrane] (Drosophila melanogaster)

Dmel\CG43066 [plasma membrane] (Drosophila melanogaster)

Slc6a15 [plasma membrane] (Mus musculus)

Slc6a15 [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001139807.1, NP_877499.1, NP_060527.2

ZINC - World Drugs

S6A15_HUMAN

Guide to Pharmacology - Targets

940

OpenTargets

ENSG00000072041

ZINC - FDA approved

S6A15_HUMAN

ZINC - Substances

S6A15_HUMAN

ZINC target

Q9H2J7

PRO

Q9H2J7

HPA

ENSG00000072041-SLC6A15

GeneCards

Q9H2J7

Ensembl

ENST00000266682, ENSP00000505731, ENST00000680963, ENSP00000450145, ENSP00000390706, ENSP00000505789, ENSP00000266682, ENST00000552192, ENSG00000072041, ENST00000681688, ENST00000681721, ENST00000450363, ENSP00000505286, ENST00000681106, ENSP00000505485

Pharos - Targets

Q9H2J7

ZINC - Predictions - Purchasable

S6A15_HUMAN

HMDB Protein

HMDBP09073

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P27824 CANX	2	CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091) CANX [endoplasmic reticulum lumen] (R-HSA-195906)	0.569	3
UniProt:Q8IXM6 NRM			0.556	3
UniProt:Q9H2L4 TMM60			0.556	3
UniProt:Q96JW4 SLC41A2	1	SLC41A2 [plasma membrane] (R-HSA-442666)	0.556	3
UniProt:Q9NVC3 S38A7			0.556	3
UniProt:O75084 FZD7	1	FZD7 [plasma membrane] (R-HSA-517394)	0.556	3
UniProt:Q8TBA6 GOLGA5	2	GOLGA5 [transport vesicle] (R-HSA-8847517) GOLGA5 [Golgi membrane] (R-HSA-8847514)	0.527	2
UniProt:O95292 VAPB	2	VAPB [endoplasmic reticulum membrane] (R-HSA-429718) VAPB [Golgi membrane] (R-HSA-9715115)	0.527	3
UniProt:Q53EU6 GPAT3	1	AGPAT9 [endoplasmic reticulum membrane] (R-HSA-549109)	0.527	2
UniProt:Q9Y3E5 PTRH2	2	PTRH2 [mitochondrial outer membrane] (R-HSA-5696909) PolyUb-PTRH2 [mitochondrial outer membrane] (R-HSA-6783190)	0.527	2
UniProt:Q03135 CAV1	5	CAV1 [Golgi membrane] (R-HSA-204504) CAV1 [plasma membrane] (R-HSA-534994) CAV1 [early endosome membrane] (R-HSA-5368451) CAV1 [lipid droplet] (R-HSA-163510) CAV1 [endocytic vesicle membrane] (R-HSA-535009)	0.527	2
UniProt:Q96CP7 TLCD1			0.527	2
UniProt:Q8TD22 SFXN5			0.527	2
UniProt:Q9NR77 PXMP2	2	PXMP2 [cytosol] (R-HSA-9603794) PXMP2 [peroxisomal membrane] (R-HSA-8953432)	0.527	2
UniProt:Q6Y1H2 HACD2	1	PTPLB [endoplasmic reticulum membrane] (R-HSA-5676075)	0.527	2
UniProt:Q8N4N3 KLH36			0.527	2
UniProt:Q8N6K0 TEX29			0.527	2
UniProt:P0DTD1-PRO_0000449624 REP			0.527	2

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