Reactome | SLC6A6-mediated uptake of taurine and beta-alanine

SLC6A6-mediated uptake of taurine and beta-alanine

Stable Identifier

R-HSA-351987

Type

Reaction [transition]

Species

Homo sapiens

Compartment

plasma membrane

ReviewStatus

5/5

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Transport of small molecules (Homo sapiens)

- SLC-mediated transmembrane transport (Homo sapiens)
  - Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
    - Na+/Cl- dependent neurotransmitter transporters (Homo sapiens)
      - SLC6A6-mediated uptake of taurine and beta-alanine (Homo sapiens)
  - Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
    - Amino acid transport across the plasma membrane (Homo sapiens)
      - SLC6A6-mediated uptake of taurine and beta-alanine (Homo sapiens)

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SLC6A6-mediated uptake of taurine and beta-alanine

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The plasma membrane transport protein SLC6A6 mediates the uptake of taurine and beta-alanine. Together with each amino acid molecule, 2 sodium ions and 1 chloride ion are taken up. SLC6A6 is widely expressed in the body (Ramamoorthy et al. 1994).

Literature References

PubMed ID	Title	Journal	Year
8010975	Functional characterization and chromosomal localization of a cloned taurine transporter from human placenta Mahesh, VB, Han, H, Leibach, FH, Ganapathy, V, Blakely, RD, Yang-Feng, T, Ramamoorthy, S	Biochem J	1994