The protein SLC6A18 was first identified as an amino acid transporter based on sequence similarity to other members of the SLC6 protein family (Hoglund et al. 2005). It is annotated here as mediating glycine uptake based on the phenotype of mice homozygous for a null mutation in the homologous gene (Quan et al. 2004).
Lindblom, J, Höglund, PJ, Scicluna, SJ, Fredriksson, R, Adzic, D
Quan, H, Caron, MG, Wetsel, WC, Athirakul, K, Stevens, R, Torres, GE, Coffman, TM
amino acid transmembrane transporter activity of SLC6A18 [plasma membrane]
© 2023 Reactome