Translocation of active caspase-8 to the mitochondrial membrane

Stable Identifier
R-HSA-351863
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, mitochondrial outer membrane
ReviewStatus
5/5
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Translocation of active caspase-8 to the mitochondrial membrane
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Active caspase 8 associates with the membranes during apoptosis caused by multiple stimuli (Chandra et al., 2004). OMM-localized active caspase 8 can activate cytosolic caspase 3 and ER-localized BAP31 (Chandra et al., 2004) .

Literature References
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Orthologous Events
Translocation of active caspase-8 to the mitochondrial membrane (Bos taurus)
Translocation of active caspase-8 to the mitochondrial membrane (Canis familiaris)
Translocation of active caspase-8 to the mitochondrial membrane (Danio rerio)
Translocation of active caspase-8 to the mitochondrial membrane (Gallus gallus)
Translocation of active caspase-8 to the mitochondrial membrane (Mus musculus)
Translocation of active caspase-8 to the mitochondrial membrane (Rattus norvegicus)
Translocation of active caspase-8 to the mitochondrial membrane (Sus scrofa)
Translocation of active caspase-8 to the mitochondrial membrane (Xenopus tropicalis)
Authored
Schulze-Osthoff, K  (2008-05-18)
Reviewed
Gillespie, ME  (2012-11-19)
Ranganathan, S  (2008-06-11)
Created
Matthews, L  (2008-05-29)
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