Reactome | AMD1(1-67) [cytosol]

AMD1(1-67) [cytosol]

Stable Identifier

R-HSA-351223

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

AdoMetDC

Locations in the PathwayBrowser for interactor UniProt:P18509 ADCYAP1

Expand all

External Reference Information

External Reference

UniProt:P17707 AMD1

Gene Names

AMD1, AMD

Chain

chain:1-67, chain:68-334

Reference Genes

BioGPS Gene:262 AMD1

COSMIC (genes):AMD1 AMD1

CTD Gene:262 AMD1

dbSNP Gene:262 AMD1

ENSEMBL:ENSG00000123505 AMD1

HGNC:457 AMD1

KEGG:hsa:262 AMD1

Monarch:262 AMD1

NCBI Gene:262 AMD1

OMIM:180980 AMD1

UCSC:P17707 AMD1

Reference Transcript

RefSeq:NM_001634.5 AMD1

Other Identifiers

11717237_s_at

11717238_a_at

11747828_x_at

11747877_x_at

11748140_s_at

11755126_s_at

11758768_x_at

17011671

201196_PM_s_at

201196_s_at

201197_PM_at

201197_at

236090_PM_at

236090_at

262

262_at

263_g_at

2855730

2921300

2921301

2921302

2921303

2921304

2921307

2921313

2921314

2921315

2921316

2921317

2921318

2921319

2921320

2921321

2921322

2921323

2921324

2921325

2921326

2921327

2921328

2921329

2921330

2921331

2921333

2921335

2921336

36684_at

36685_at

75280_r_at

8121489

A_14_P133699

A_23_P214121

A_24_P371962

A_33_P3395369

GE61981

GO:0003824

GO:0004014

GO:0005515

GO:0005829

GO:0006595

GO:0006597

GO:0008295

GO:0016829

GO:0016831

GO:0019810

GO:0042802

HMNXSV003007123

HMNXSV003046568

Hs.140546.0.A1_3p_at

ILMN_1667994

ILMN_1788462

M21154_at

PH_hs_0022749

PH_hs_0031912

TC06000883.hg

g178517_3p_a_at

g5209326_3p_at

Inferred To

SPE2 [cytosol] (Saccharomyces cerevisiae)

spe2 [cytosol] (Schizosaccharomyces pombe)

amd1 [cytosol] (Dictyostelium discoideum)

amd1 [cytosol] (Xenopus tropicalis)

AMD1 [cytosol] (Canis familiaris)

AMD1 [cytosol] (Sus scrofa)

SamDC [cytosol] (Drosophila melanogaster)

AMD1(1-67) [cytosol] (Bos taurus)

AMD1(1-67) [cytosol] (Danio rerio)

AMD1(1-67) [cytosol] (Gallus gallus)

AMD1(1-67) [cytosol] (Mus musculus)

AMD1(1-67) [cytosol] (Rattus norvegicus)

smd-1 [cytosol] (Caenorhabditis elegans)

Cross References

ZINC - World Drugs

DCAM_HUMAN

Guide to Pharmacology - Targets

1269

OpenTargets

ENSG00000123505

ENSEMBL

ENSP00000357880, ENST00000368885

ZINC - Substances

DCAM_HUMAN

ZINC - Biogenic

DCAM_HUMAN

ZINC target

P17707

PRO

P17707

PDB

1JL0, 1MSV, 1I79, 1I72, 3DZ2, 3EP6, 3DZ3, 3EP7, 3DZ4, 3EP8, 3DZ5, 3EP9, 3DZ6, 3EP3, 3H0V, 3DZ7, 3EP4, 3H0W, 3EP5, 1I7C, 1JEN, 1I7B, 3EPA, 3EPB, 1I7M

ZINC - Investigational

DCAM_HUMAN

ZINC - Metabolites

DCAM_HUMAN

IntEnz

4.1.1.50

HPA

ENSG00000123505-AMD1

Pharos - Targets

P17707

ZINC - Predictions - Purchasable

DCAM_HUMAN

HMDB Protein

HMDBP00420

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96A98 PTH2	1	PTH2(62-100) [extracellular region] (R-HSA-420572)	0.589	2
UniProt:P17707 AMD1	1	AMD1(1-67) [cytosol] (R-HSA-351223)	0.556	3
UniProt:Q8WY91 THAP4			0.556	3
UniProt:P18509 ADCYAP1	4	ADCYAP1(132-158) [extracellular region] (R-HSA-420144) ADCYAP1(82-129) [extracellular region] (R-HSA-420254) ADCYAP1(132-169) [extracellular region] (R-HSA-420282) ADCYAP1(2-742) [Golgi membrane] (R-HSA-187679)	0.527	2
UniProt:Q9NZD2 GLTP	1	GLTP [cytosol] (R-HSA-5216109)	0.527	2
UniProt:Q96HB5 CC120			0.527	2
UniProt:Q9Y240 CLC11			0.527	3
UniProt:Q9Y664 KPTN	1	KPTN [lysosomal membrane] (R-HSA-9638238)	0.527	2
UniProt:Q9UKT5 FBXO4	1	FBXO4 [cytosol] (R-HSA-391298)	0.527	2
UniProt:O95707 POP4	1	POP4 [nucleoplasm] (R-HSA-5696789)	0.527	2
UniProt:P01189 POMC	12	POMC(237-241) [extracellular region] (R-HSA-167407) POMC(237-267) [extracellular region] (R-HSA-167405) POMC(138-176) [extracellular region] (R-HSA-388607) POMC(138-150) [extracellular region] (R-HSA-388593) POMC(217-234) [extracellular region] (R-HSA-388617) POMC(77-87) [extracellular region] (R-HSA-388618) POMC(138-176) [cytosol] (R-HSA-1502544) POMC(138-176) K25* [extracellular region] (R-HSA-5623536) POMC(138-176) E79* [extracellular region] (R-HSA-5623539) POMC(138-176) R236G [extracellular region] (R-HSA-5603387) POMC(1-241) [secretory granule lumen] (R-HSA-378943) POMC(138-176) [secretory granule lumen] (R-HSA-378965)	0.527	2
UniProt:P51888 PRELP	11	N-glycan PRELP [Golgi lumen] (R-HSA-2046156) Gal-glycan PRELP [Golgi lumen] (R-HSA-2046279) Keratan(1)-PRELP [Golgi lumen] (R-HSA-2046292) Keratan(2)-PRELP [Golgi lumen] (R-HSA-2046219) Keratan(3)-PRELP [Golgi lumen] (R-HSA-2046159) Keratan(4)-PRELP [Golgi lumen] (R-HSA-2046276) KS(2)-PRELP [Golgi lumen] (R-HSA-2046160) KS(1)-PRELP [Golgi lumen] (R-HSA-2046258) KS(2)-PRELP [extracellular region] (R-HSA-2046162) PRELP [lysosomal lumen] (R-HSA-2105006) KS(2)-PRELP [lysosomal lumen] (R-HSA-2046286)	0.527	2
UniProt:Q8IVT2 MISP			0.527	2
UniProt:O95972 BMP15	2	p-BMP15 [endoplasmic reticulum lumen] (R-HSA-8957002) BMP15 [endoplasmic reticulum lumen] (R-HSA-8956729)	0.527	2
UniProt:Q9UK85 DKKL1			0.527	3
UniProt:Q96DB2 HDAC11	1	HDAC11 [nucleoplasm] (R-HSA-351590)	0.527	2
UniProt:Q969T3 SNX21			0.527	2

Cite Us!