Reactome | N-acetylated spermidine (cytosol)=>N-acetylated spermidine (peroxisomal)

N-acetylated spermidine (cytosol)=>N-acetylated spermidine (peroxisomal)

Stable Identifier

R-HSA-351201

Type

Reaction [transition]

Species

Homo sapiens

Compartment

cytosol

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N-acetylated spermidine (cytosol)=>N-acetylated spermidine (peroxisomal)

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The N1-acetylation of spermidine and spermine by spermidine/spermine acetyltransferase (SSAT) is a crucial step in the regulation of the cellular polyamine levels in eukaryotic cells. The kinetics of this enzyme has been already elucidated (Hedge et al. 2007).

Literature References

PubMed ID	Title	Journal	Year
17516632	Mechanistic and structural analysis of human spermidine/spermine N1-acetyltransferase Hegde, SS, Chandler, J, Vetting, MW, Yu, M, Blanchard, JS	Biochemistry	2007