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DIO3 [plasma membrane]
Stable Identifier
R-HSA-350873
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Type III iodothyronine deiodinase
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Metabolism of amine-derived hormones (Homo sapiens)
Thyroxine biosynthesis (Homo sapiens)
Regulation of thyroid hormone activity (Homo sapiens)
Thyroxine is deiodinated to reverse triiodothyronine (RT3) (Homo sapiens)
DIO3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P55073 DIO3
Gene Names
DIO3, ITDI3, TXDI3
Chain
chain:1-304
Reference Genes
BioGPS Gene:1735 DIO3
COSMIC (genes):DIO3 DIO3
CTD Gene:1735 DIO3
dbSNP Gene:1735 DIO3
ENSEMBL:ENSG00000197406 DIO3
HGNC:2885 DIO3
KEGG:hsa:1735 DIO3
Monarch:1735 DIO3
NCBI Gene:1735 DIO3
OMIM:601038 DIO3
UCSC:P55073 DIO3
Reference Transcript
RefSeq:NM_001362.3 DIO3
Other Identifiers
11730329_a_at
11730330_a_at
16788821
1735
207154_PM_at
207154_at
34591_at
3552686
3552687
3552688
3552689
3552690
3552691
3552692
3552693
7976858
A_14_P115316
A_23_P105923
A_33_P3246513
GE58819
GO:0001666
GO:0003824
GO:0004800
GO:0005768
GO:0005886
GO:0006575
GO:0006915
GO:0010008
GO:0012501
GO:0016491
GO:0031410
GO:0033798
GO:0040018
GO:0042403
GO:0042404
GO:0042446
GO:0043226
GO:0043231
GO:0046549
GO:0048856
GO:0070342
GO:0097474
HMNXSV003052733
ILMN_2075067
PH_hs_0003436
S79854_at
TC14000771.hg
g4503334_3p_at
Inferred To
DIO3 [plasma membrane]
(Bos taurus)
DIO3 [plasma membrane]
(Sus scrofa)
dio3 [plasma membrane]
(Dictyostelium discoideum)
Dio3 [plasma membrane]
(Mus musculus)
Dio3 [plasma membrane]
(Rattus norvegicus)
Homologues of DIO3 [plasma membrane]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
2483
ENSEMBL
ENST00000510508
,
ENSP00000427336
,
ENSG00000197406
OpenTargets
ENSG00000197406
IntEnz
1.21.99.3
GeneCards
DIO3
HPA
ENSG00000197406-DIO3
ZINC - Substances
IOD3_HUMAN
ZINC target
P55073
PRO
P55073
Pharos - Targets
P55073
HMDB Protein
HMDBP09381
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