Regulation of thyroid hormone activity

Stable Identifier
R-HSA-350864
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Regulation of thyroid hormone activity
Click the image above or here to open this pathway in the Pathway Browser
Production and secretion of the thyroid hormone T3 and its inactive precursor T4 by thyroid follicular cells is regulated by Thyroid-stimulating hormone (TSH, thyrotropin) signalling and several feedback loops involving iodine and thyroglobulin (reviewed in Köhrle, 1999; Kleinau et al., 2013; Jing & Zhang, 2022).
Literature References
PubMed ID Title Journal Year
17016550 Deiodinases: implications of the local control of thyroid hormone action

Bianco, AC, Kim, BW

J Clin Invest 2006
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
thyroid hormone metabolic process (0042403)
Orthologous Events
Regulation of thyroid hormone activity (Bos taurus)
Regulation of thyroid hormone activity (Canis familiaris)
Regulation of thyroid hormone activity (Dictyostelium discoideum)
Regulation of thyroid hormone activity (Gallus gallus)
Regulation of thyroid hormone activity (Mus musculus)
Regulation of thyroid hormone activity (Rattus norvegicus)
Regulation of thyroid hormone activity (Sus scrofa)
Regulation of thyroid hormone activity (Xenopus tropicalis)
Authored
Jassal, B  (2008-10-01)
Reviewed
D'Eustachio, P  (2008-05-28)
Created
Jassal, B  (2008-05-21)
Cite Us!