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AP1S3 [Golgi membrane]
Stable Identifier
R-HSA-350806
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
AP-1 sigma 1C
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
trans-Golgi Network Vesicle Budding (Homo sapiens)
Golgi Associated Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP-1 sigma [Golgi membrane] (Homo sapiens)
AP1S3 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Coat Assembly (Homo sapiens)
Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP-1 sigma [Golgi membrane] (Homo sapiens)
AP1S3 [Golgi membrane] (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP-1 sigma [Golgi membrane] (Homo sapiens)
AP1S3 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Vesicle Scission (Homo sapiens)
Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP-1 sigma [Golgi membrane] (Homo sapiens)
AP1S3 [Golgi membrane] (Homo sapiens)
Lysosome Vesicle Biogenesis (Homo sapiens)
Vamp And trans-Golgi Network AP-1 Binding Coupled With Cargo Capture On Lysosome Vesicle Destined Golgi Membrane (Homo sapiens)
Lysosome Destined Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP-1 sigma [Golgi membrane] (Homo sapiens)
AP1S3 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Lysosomal Vesicle Scission (Homo sapiens)
Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP-1 sigma [Golgi membrane] (Homo sapiens)
AP1S3 [Golgi membrane] (Homo sapiens)
trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Homo sapiens)
Lysosome Destined Cargo:AP-1:Arf1-GTP:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP-1 sigma [Golgi membrane] (Homo sapiens)
AP1S3 [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Homo sapiens)
Lysosome Destined Cargo:AP-1:beta-Arrestin-1:Vamp Complex [Golgi membrane] (Homo sapiens)
AP-1 Complex [Golgi membrane] (Homo sapiens)
AP-1 sigma [Golgi membrane] (Homo sapiens)
AP1S3 [Golgi membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96PC3 AP1S3
Gene Names
AP1S3
Chain
chain:1-154
Reference Genes
BioGPS Gene:130340 AP1S3
COSMIC (genes):AP1S3 AP1S3
CTD Gene:130340 AP1S3
dbSNP Gene:130340 AP1S3
ENSEMBL:ENSG00000152056 AP1S3
HGNC:18971 AP1S3
KEGG:hsa:130340 AP1S3
Monarch:130340 AP1S3
NCBI Gene:130340 AP1S3
OMIM:615781 AP1S3
UCSC:Q96PC3 AP1S3
Reference Transcript
RefSeq:NM_001039569.1 AP1S3
Other Identifiers
11732496_a_at
11753670_a_at
11761673_at
130340
1555731_PM_a_at
1555731_a_at
1555733_PM_s_at
1555733_s_at
1555734_PM_x_at
1555734_x_at
16908985
237159_PM_x_at
237159_x_at
2437245
2601259
2601278
2601279
2601280
2601281
2601284
2601291
2601296
2601297
2601298
2601299
2601300
2601301
2601302
2601303
2601304
2601305
2601306
2601308
2601309
2601310
2601312
2601313
2601314
2601316
2601321
2601322
67062_r_at
68310_at
8059350
A_19_P00315870
A_19_P00317925
A_19_P00318120
A_19_P00318706
A_19_P00319888
A_19_P00319889
A_19_P00320725
A_19_P00322071
A_23_P385295
A_24_P105747
A_33_P3275707
A_33_P3288995
A_33_P3289000
A_33_P3289005
GE88097
GO:0000139
GO:0005515
GO:0005737
GO:0005765
GO:0005768
GO:0005769
GO:0005794
GO:0005829
GO:0005905
GO:0006605
GO:0006886
GO:0015031
GO:0016020
GO:0016192
GO:0030117
GO:0030121
GO:0030659
GO:0031410
GO:0032588
GO:0035615
GO:0043226
GO:0043231
GO:0060090
GO:0060155
GO:1903232
HMNXSV003052107
Hs2.348666.3.S1_3p_a_at
Hs2.348666.3.S1_3p_x_at
ILMN_1768610
PH_hs_0024431
TC02002819.hg
TC02004830.hg
Participates
as a member of
AP-1 sigma [Golgi membrane] (Homo sapiens)
Other forms of this molecule
AP1S3 [cytosol]
AP1S3 [trans-Golgi network membrane]
AP1S3 [lysosomal membrane]
AP1S3 [cytoplasmic vesicle membrane]
Inferred To
wu:fj40d12 [Golgi membrane]
(Danio rerio)
APS1 [Golgi membrane]
(Saccharomyces cerevisiae)
ap1s3 [Golgi membrane]
(Xenopus tropicalis)
AP-1sigma [Golgi membrane]
(Drosophila melanogaster)
ap1s1 [Golgi membrane]
(Dictyostelium discoideum)
Ap1s3 [Golgi membrane]
(Mus musculus)
Ap1s3 [Golgi membrane]
(Rattus norvegicus)
ap1s2 [Golgi membrane]
(Danio rerio)
ap1s2 [Golgi membrane]
(Dictyostelium discoideum)
AP1S3 [Golgi membrane]
(Bos taurus)
AP1S3 [Golgi membrane]
(Gallus gallus)
AP1S3 [Golgi membrane]
(Sus scrofa)
aps-1 [Golgi membrane]
(Caenorhabditis elegans)
Homologues of AP1S3 [Golgi membrane]
(Danio rerio)
Homologues of AP1S3 [Golgi membrane]
(Dictyostelium discoideum)
Cross References
OpenTargets
ENSG00000152056
ENSEMBL
ENST00000443700
,
ENSP00000379891
,
ENSP00000401705
,
ENSP00000388738
,
ENST00000396654
,
ENSG00000152056
,
ENSP00000397155
,
ENST00000446015
,
ENST00000415298
HPA
ENSG00000152056-AP1S3
GeneCards
AP1S3
PRO
Q96PC3
Pharos - Targets
Q96PC3
Orphanet
AP1S3
PDB
6CM9
,
6DFF
,
8D9T
,
8D4C
,
7UX3
,
8D4D
,
8D4F
,
7R4H
,
8D4E
,
8D4G
,
4HMY
,
8D9W
,
8D9U
,
6D83
,
8D9R
,
8D9V
,
6CRI
,
8D9S
,
6D84
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