Caspase-mediated cleavage of MASK

Stable Identifier
R-HSA-350651
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Caspase-mediated cleavage of MASK
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MASK is cleaved in vitro by caspase 3 . C-terminally truncated forms of MASK can both induce apoptosis upon overexpression in mammalian cells (Dan et al., 2002).
Literature References
PubMed ID Title Journal Year
11741893 Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing properties

Kristiansen, TZ, Ong, SE, Pandey, A, Kajikawa, E, Mann, M, Nielsen, MM, Blagoev, B, Watanabe, NM, Dan, I

J Biol Chem 2002
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as an event of
Catalyst Activity

cysteine-type endopeptidase activity of Caspase-3 [cytosol]

Physical Entity
Caspase-3 [cytosol] (Homo sapiens)
Activity
cysteine-type endopeptidase activity (GO:0004197)
Orthologous Events
Caspase-mediated cleavage of MASK (Bos taurus)
Caspase-mediated cleavage of MASK (Canis familiaris)
Caspase-mediated cleavage of MASK (Danio rerio)
Caspase-mediated cleavage of MASK (Gallus gallus)
Caspase-mediated cleavage of MASK (Mus musculus)
Caspase-mediated cleavage of MASK (Rattus norvegicus)
Caspase-mediated cleavage of MASK (Sus scrofa)
Caspase-mediated cleavage of MASK (Xenopus tropicalis)
Authored
Schulze-Osthoff, K  (2008-05-18)
Reviewed
Ranganathan, S  (2008-06-11)
Created
Matthews, L  (2008-05-20)
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