As it hydrolyzes a guanidino group within agmatine and also contains signature amino acid residues that act as ligand binding sites for the potential Mn(++) cofactor, agmatinase is classified as a member of the arginase superfamily (Morris, 2003).
Iyer, RK, Cederbaum, SD, Tsoa, RW, Kim, HK, Grody, WW
Cook, WJ, Burwell, TJ, Mistry, SK, Morris SM, Jr, Chambers, RM, Rudolph-Owen, L, Spaltmann, F
agmatinase activity of AGMAT(1-?) [mitochondrion]
© 2023 Reactome