Agmatine is polyamine formed by decarboxylation of L-arginine by arginine decarboxylase (ADC). Human ADC is a 460-amino acid protein that shows about 48% identity to mammalian ornithine decarboxylase (ODC) but has no ODC activity.
Zhu, MY, Piletz, JE, Iyo, A, Regunathan, S
arginine decarboxylase activity of ADC [cytosol]
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