Reactome | SIN3B-1 [nucleoplasm]

SIN3B-1 [nucleoplasm]

Stable Identifier

R-HSA-349685

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

SIN3B_HUMAN, Paired amphipathic helix protein Sin3b, SIN3B isoform 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O75182-1 SIN3B

Gene Names

SIN3B, KIAA0700

Participates

as a member of

Corepressors of PPARalpha [nucleoplasm] (Homo sapiens)

Inferred To

Sin3A [nucleoplasm] (Drosophila melanogaster)

pst3 [nucleoplasm] (Schizosaccharomyces pombe)

SIN3 [nucleoplasm] (Saccharomyces cerevisiae)

SIN3B [nucleoplasm] (Bos taurus)

SIN3B [nucleoplasm] (Canis familiaris)

SIN3B [nucleoplasm] (Gallus gallus)

SIN3B [nucleoplasm] (Sus scrofa)

SIN3B-1 [nucleoplasm] (Dictyostelium discoideum)

Homologues of SIN3B-1 [nucleoplasm] (Schizosaccharomyces pombe)

sin3b [nucleoplasm] (Danio rerio)

sin3b [nucleoplasm] (Xenopus tropicalis)

pst1 [nucleoplasm] (Schizosaccharomyces pombe)

sin-3 [nucleoplasm] (Caenorhabditis elegans)

Sin3b [nucleoplasm] (Mus musculus)

Sin3b [nucleoplasm] (Rattus norvegicus)

pst2 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_001284526.1, NP_056075.1, NP_001284524.1

ENSEMBL

ENSG00000127511, ENST00000379803, ENSP00000369131, ENSP00000473039, ENSP00000248054, ENST00000248054, ENST00000596802

OpenTargets

ENSG00000127511

GeneCards

SIN3B

HPA

ENSG00000127511-SIN3B

PRO

O75182

Pharos - Targets

O75182

GlyGen

O75182

PDB

8BPB, 8BPC, 8BPA, 8C60

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.788	7
UniProt:Q92769 HDAC2	2	HDAC2 [nucleoplasm] (R-HSA-205135) monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958)	0.643	3
UniProt:Q09028 RBBP4	1	RBBP4 [nucleoplasm] (R-HSA-212223)	0.643	5
UniProt:Q16576 RBBP7	1	RBBP7 [nucleoplasm] (R-HSA-212227)	0.643	5
UniProt:P01106 MYC	2	MYC [nucleoplasm] (R-HSA-188379) PolyUb-MYC [nucleoplasm] (R-HSA-6783169)	0.607	7
UniProt:Q9UER7 DAXX	13	DAXX [nucleoplasm] (R-HSA-3222068) DAXX A36Qfs108 [nucleoplasm] (R-HSA-9673105) DAXX K56 [nucleoplasm] (R-HSA-9673089) DAXX A103Sfs40 [nucleoplasm] (R-HSA-9673121) DAXX C106 [nucleoplasm] (R-HSA-9673079) DAXX E72Nfs72 [nucleoplasm] (R-HSA-9673110) DAXX E104 [nucleoplasm] (R-HSA-9673078) DAXX H26Tfs118 [nucleoplasm] (R-HSA-9673114) DAXX S138 [nucleoplasm] (R-HSA-9673081) DAXX C74* [nucleoplasm] (R-HSA-9673096) DAXX R48Vfs93 [nucleoplasm] (R-HSA-9673103) DAXX L98Vfs13 [nucleoplasm] (R-HSA-9673102) monoSUMO1-K630,K631-DAXX [nucleoplasm] (R-HSA-4086086)	0.527	4
UniProt:Q96ST3 SIN3A	2	SIN3A [nucleoplasm] (R-HSA-351657) monoSUMO1-SIN3A [nucleoplasm] (R-HSA-4086071)	0.527	2

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