Reactome | SCARB1-2 [plasma membrane]

SCARB1-2 [plasma membrane]

Stable Identifier

R-HSA-349415

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

SR-BI, Scavenger receptor class B member 1

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8WTV0-2 SCARB1

Gene Names

SCARB1, CD36L1, CLA1

Other Identifiers

11728298_a_at

11756522_a_at

1552256_PM_a_at

1552256_a_at

16772144

201819_PM_at

201819_at

215834_PM_x_at

3476685

3476686

3476687

3476688

3476689

3476690

3476691

3476697

3476702

3476703

3476704

3476707

3476709

3476710

3476713

3476714

3476715

3476716

3476717

3476718

3476731

3476732

41200_at

7967544

949

A_23_P203900

A_23_P369201

A_24_P324565

GE81521

GO:0001530

GO:0001540

GO:0001618

GO:0001786

GO:0001875

GO:0001935

GO:0005044

GO:0005515

GO:0005545

GO:0005576

GO:0005615

GO:0005737

GO:0005764

GO:0005765

GO:0005773

GO:0005886

GO:0005901

GO:0006629

GO:0006707

GO:0006869

GO:0008035

GO:0008289

GO:0009986

GO:0010595

GO:0010867

GO:0010886

GO:0010899

GO:0015914

GO:0015920

GO:0016020

GO:0016192

GO:0022600

GO:0023052

GO:0030169

GO:0030301

GO:0030666

GO:0031410

GO:0031663

GO:0032497

GO:0033344

GO:0034185

GO:0034186

GO:0034375

GO:0034381

GO:0034383

GO:0034384

GO:0035461

GO:0038024

GO:0042060

GO:0042632

GO:0043226

GO:0043231

GO:0043534

GO:0043654

GO:0043691

GO:0044406

GO:0046718

GO:0046867

GO:0048870

GO:0050764

GO:0051000

GO:0055085

GO:0060089

GO:0070062

GO:0070328

GO:0070506

GO:0070508

GO:0098856

HMNXSV003002143

ILMN_2183409

PH_hs_0022454

TC12002097.hg

Z22555_at

g5031628_3p_s_at

Participates

as an input of

as an output of

Disassembly of SR-BI-bound spherical HDL (Homo sapiens)

as a component of

Other forms of this molecule

SCARB1-2 [endocytic vesicle membrane]

Inferred To

Homologues of SCARB1-2 [plasma membrane] (Dictyostelium discoideum)

Homologues of SCARB1-2 [plasma membrane] (Sus scrofa)

SCARB1 [plasma membrane] (Bos taurus)

SCARB1 [plasma membrane] (Canis familiaris)

SCARB1 [plasma membrane] (Gallus gallus)

SCARB1 [plasma membrane] (Sus scrofa)

lmpA [plasma membrane] (Dictyostelium discoideum)

lmpC [plasma membrane] (Dictyostelium discoideum)

crq [plasma membrane] (Drosophila melanogaster)

scarb1 [plasma membrane] (Xenopus tropicalis)

Scarb1 [plasma membrane] (Mus musculus)

Scarb1 [plasma membrane] (Rattus norvegicus)

lmpB [plasma membrane] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001076428.1, NP_005496.4

OpenTargets

ENSG00000073060

ZINC - Substances

SCRB1_HUMAN

ZINC target

Q8WTV0

PRO

Q8WTV0

ZINC - Investigational

SCRB1_HUMAN

HPA

ENSG00000073060-SCARB1

GeneCards

Q8WTV0

Ensembl

ENSG00000073060, ENST00000415380, ENST00000261693, ENSP00000261693, ENSP00000414979, ENST00000339570, ENSP00000343795

Pharos - Targets

Q8WTV0

Orphanet

24885

ZINC - Predictions - Purchasable

SCRB1_HUMAN

HMDB Protein

HMDBP02237

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.556	3

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